About the Project
The project will exploit the availability of a tomato mutant that is defective in this process and will address the fundamental problem of how plant cells communicate. Identifying the defect in this mutant will allow us to identify how adjacent cells transmit spatial information and how this information is used to direct the deposition of the secondary cell wall. Understanding this process will help us to more effectively engineer plants with increased biomass for bioprocessing while ensuring that plant growth and development is not compromised.
This is a multidisciplinary project involving the use of molecular genetics that will exploit the latest developments in both next generation sequencing and live cell imaging.
Applicants must have obtained, or be about to obtain, at least an upper second class honours degree (or equivalent) in a relevant subject.
UK applicants interested in this project should make direct contact with the Principal Supervisor to arrange to discuss the project further as soon as possible. International applicants (including EU nationals) must ensure they meet the academic eligibility criteria (including English Language) as outlined before contacting potential supervisors to express an interest in their project. Eligibility can be checked via the University Country Specific information page (https://www.manchester.ac.uk/study/international/country-specific-information/).
If your country is not listed you must contact the Doctoral Academy Admissions Team providing a detailed CV (to include academic qualifications – stating degree classification(s) and dates awarded) and relevant transcripts.
Following the review of your qualifications and with support from potential supervisor(s), you will be informed whether you can submit a formal online application.
To be considered for this project you MUST submit a formal online application form - full details on how to apply can be found on the BBSRC DTP website www.manchester.ac.uk/bbsrcdtpstudentships
Equality, diversity and inclusion is fundamental to the success of The University of Manchester, and is at the heart of all of our activities. The full Equality, diversity and inclusion statement can be found on the website https://www.bmh.manchester.ac.uk/study/research/apply/equality-diversity-inclusion/
Kumar, M., Wightman, R., Atanassov, I., Gupta, A., Hurst, C.H., Hemsley, P.A., and Turner, S. (2016). S-Acylation of the cellulose synthase complex is essential for its plasma membrane localization. Science 353, 166-169.
Kumar, M., Mishra, L., Carr, P., Pilling, M., Gardner, P., Mansfield, S.D., and Turner, S.R. (2018). Exploiting CELLULOSE SYNTHASE (CESA) class-specificity to probe cellulose microfibril biosynthesis. Plant Physiol. 177, 151-167.
Smit, M.E., McGregor, S.R., Sun, H., Gough, C., Bagman, A.M., Soyars, C.L., Kroon, J.T., Gaudinier, A., Williams, C.J., Yang, X.Y., Nimchuk, Z.L., Weijers, D., Turner, S.R., Brady, S.M., and Etchells, J.P. (2020). A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Plant Cell 32, 319-335.
Wang, N., Bagdassarian, K.S., Doherty, R.E., Kroon, J.T., Connor, K.A., Wang, X.Y., Wang, W., Jermyn, I.H., Turner, S.R., and Etchells, J.P. (2019). Organ-specific genetic interactions between paralogues of the PXY and ER receptor kinases enforce radial patterning in Arabidopsis vascular tissue. Development 146, dev177105.
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