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(BBSRC DTP) Neural circuit mechanisms of sensory perception

Project Description

The cerebral cortex has long been known to be a critical part of the brain’s computational machinery: damage to it, through stroke or neurodegeneration, causes severe deficits of perception and cognition. However, we still have a poor understanding of how the cortex works, hampered by the past difficulty of measuring from more than one neuron at the same time. Excitingly, very powerful experimental methods (microelectrode array electrophysiology and multi-photon Calcium imaging) have recently been developed that make it possible to measure the activity of 100s /1000s of cortical neurons at the same time, and thereby to get insight into how neural circuits work at the population level. The aim of this project is investigate cortical circuit mechanisms of perception by using the whisker system as a model.

This project could suit motivated students from either a biology/neuroscience background or from a physical sciences background. The successful student will have the opportunity to investigate this question using in vivo electrophysiology and multi-photon Calcium imaging. They will also have the chance to learn to analyse the data by means of computational methods.

Entry Requirements:
Applications are invited from UK/EU nationals only. Applicants must have obtained, or be about to obtain, at least an upper second class honours degree (or equivalent) in a relevant subject.

Funding Notes

This project is to be funded under the BBSRC Doctoral Training Partnership. If you are interested in this project, please make direct contact with the Principal Supervisor to arrange to discuss the project further as soon as possible. You MUST also submit an online application form - full details on how to apply can be found on the BBSRC DTP website View Website

As an equal opportunities institution we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

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