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BBSRC White Rose DTP Studentship - Role of cytidine deaminase in (epi)genetic adaptation of the plant immune system.


Project Description

As sessile organisms, plants are masters in adapting to environmental stresses. Recent work from the Ton lab has shown that plants employ epigenetic mechanisms to prime their immune system long-term against potential pests and diseases. This PhD project will study the interplay between epigenetic and genetic mechanisms controlling expression and diversification of resistance (R) genes in the model plant species Arabidopsis thaliana. In particular, the project will focus on the role of the Arabidopsis cytidine deaminase CDA1 in the modulation of epigenetic marks and its impact on genetic diversity. The student will use state-of-the art genetic and molecular techniques, and work in a highly dynamic lab that combines fundamental research with translational research to develop new technologies that benefit sustainable crop protection.

Funding Notes

- a tax-free stipend at the standard Research Council rate (~£15,009, to be confirmed for 2020) for 4 years
- tuition fees at the UK/EU rate for 4 years.
- research costs

At least a 2:1 honours degree in a relevant subject or equivalent. The interdisciplinary nature of this programme means that we welcome applications from students with backgrounds in any biological, chemical, and/or physical science, students with mathematical backgrounds who are interested in using their skills in addressing biological questions.

Studentships are available to UK and EU students who meet the UK residency requirements. Further information on eligibility: View Website.

How good is research at University of Sheffield in Biological Sciences?

FTE Category A staff submitted: 44.90

Research output data provided by the Research Excellence Framework (REF)

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