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  Bio-photonic and molecular characterization of gastric cancer tissue to improve early diagnosis


   York Biomedical Research Institute

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  Dr Manish Chauhan, Dr Andrew Mason  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

Gastric Cancer is the fifth most common malignancy in the world and third leading cause of death: 865,000 worldwide in 2017; 12 lives/day in the UK (2016-2018). According to the International Agency for Research on Cancer, 89% of all cases are attributed to infection from Helicobacter pylori (Hp). We propose to use Raman and FTIR spectroscopy to obtain vibrational and absorption spectroscopic data from gastric cancers tissues. The optical characterization of gastric cancer will be further augmented with genomic and/or transcriptomic characterization of the gastric cancer tissues; elucidating the biological processes which underpin changes in bio-photonic states.

This PhD project will combine the tissue-level molecular (at Biology department) and bio-photonic characterisations with the School of PET, with the eventual aim of developing a robot-assisted bio-photonic medical device for early detection of gastric cancer.

The York Biomedical Research Institute at the University of York is committed to recruiting extraordinary future scientists regardless of age, ethnicity, gender, gender identity, disability, sexual orientation, religion/belief, marital status, pregnancy and maternity, or career pathway to date. We understand that commitment and excellence can be shown in many ways and have built our recruitment process to reflect this. We welcome applicants from all backgrounds, particularly those underrepresented in science, who have curiosity, creativity and a drive to learn new skills.


Biological Sciences (4) Chemistry (6) Engineering (12)

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 About the Project