About the Project
This project will investigate how cell signalling enacts cellular changes. It will examine in detail how certain signalling molecules (such as peptide hormones) stimulate a response within a cell. It will look into what pathways are activated and what the downstream effects of these pathways are. It will also look into how the structure of signalling molecules is related to the response it generates within cells, and whether altering the structure alters the downstream effects. Finally, it will look at the receptors for signalling molecules and how they generate a physiological response as well as how altering their structure can cause pathological responses. This will involve a wide variety of cell biology techniques including flow cytometry, multi-mode cell signalling analysis and cell imaging. It will also provide training in standard laboratory techniques such as cell culture, immunocytochemistry, western blotting and other cellular assays. "
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