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  Biology of Ageing and Rejuvenation


   School of Physics and Astronomy

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  Prof Joao Pedro Magalhaes  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

We are seeking talented, motivated students with a passion for research in the biology of ageing to join the Genomics of Ageing and Rejuvenation Lab led by Prof Joao Pedro de Magalhaes (https://rejuvenomicslab.com/). Applicants should have a first or upper second-class degree in a relevant scientific discipline, and who are self-funded or have typically applied for, or secured funding for their studies from their government, employer or associated charitable organisations.

The goal of our lab is to develop innovative research on the biology of ageing, in particular in the context of large-scale -omics approaches. We use different methods combining experimental, theoretical, and computational approaches.

Experimentally, we have extensive experience in mammalian cell biology and molecular techniques. We have worked with various animal models, though we are not restricted to one model system and students may develop their own independent research projects. A multidisciplinary outlook and collaborations are encouraged.

We are located in the Institute of Inflammation and Ageing, part of the College of Medical and Dental Sciences, at the University of Birmingham. Situated in the largest healthcare region in the country, we have state-of-the-art facilities and equipment to support our research needs, including in cell and molecular biology, genomics, epigenetics and bioinformatics.

APPLICATION ROUTES

Self-funded or scholarship-funded graduates interested in joining our lab can select one of two different routes for undertaking a PhD in the field of Inflammation and Ageing.

Applicants with research experience and/or Master’s degree should apply directly to the Institute of Inflammation and Ageing for either a 3 or 4 year full-time PhD – https://www.birmingham.ac.uk/postgraduate/courses/research/med/inflammation-ageing.aspx

This route requires applicants to submit a drafted research proposal.

Applicants seeking additional research experience or who have yet to complete a Master’s degree should apply to the 4 year Integrated Doctoral Training Programme in Life Sciences for Health, which combined a MRes and PhD – https://www.birmingham.ac.uk/postgraduate/pgr/idtp/index.aspx

Applicants will need to submit the following documentation during the application process.

• Detailed CV, including your nationality and country of birth;

• Covering letter highlighting your research experience/capabilities and why you wish to undertake a PhD in the team;

• Names and addresses of two referees;

• Copies of your degree certificates with transcripts written in English;

• Evidence of your proficiency in the English language, if applicable.

• Evidence of scholarship application/funding or independent funding.

ADDITIONAL INFORMATION

University of Birmingham offers pre-sessional English Language courses through the Birmingham International Academy – https://www.birmingham.ac.uk/international/bia/presessional/index.aspx

For additional information on postgraduate studying at University of Birmingham please click - https://www.birmingham.ac.uk/study/postgraduate

For additional information on research at the College of Medical and Dental Sciences please click – https://www.birmingham.ac.uk/research/activity/mds/index.aspx

For additional information on research in the Institute of Inflammation and Ageing please click – https://www.birmingham.ac.uk/research/inflammation-ageing/index.aspx

For additional information on the Genomics of Ageing and Rejuvenation Lab please click - https://rejuvenomicslab.com/

For additional information on Prof de Magalhaes please click - https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/magalhaes-pedro.aspx

Biological Sciences (4)

Funding Notes

Applicants are invited from self-funded or scholarship-funded graduates only.
Applicants will be self-funded or will have typically applied for, or secured funding for their studies from their government, employer or associated charitable organisations.
Overseas graduates require IELTs of 6.5 overall.
Applying directly to the Institute of Inflammation and Ageing for either a 3 or 4 year full-time PhD – https://www.birmingham.ac.uk/postgraduate/courses/research/med/inflammation-ageing.aspx
Applying to the 4 year Integrated Doctoral Training Programme in Life Sciences for Health, which combined a MRes and PhD – https://www.birmingham.ac.uk/postgraduate/pgr/idtp/index.aspx

References

de Magalhães JP (2022) “The genetics of a long life.” Science 377:1489-1490.
de Magalhães JP, Ocampo A (2022) “Cellular reprogramming and the rise of rejuvenation biotech.” Trends in Biotechnology Trends in Biotechnology 40:639-642.
Chatsirisupachai K et al. (2021) “An integrative analysis of the age-associated multi-omic landscape across cancers.” Nature Communications 12:2345.
Fabris F et al. (2020) "Using deep learning to associate human genes with age-related diseases." Bioinformatics 36:2202-2208.
Avelar RA et al. (2020) "A multidimensional systems biology analysis of cellular senescence in ageing and disease." Genome Biology 21:91.
TEDx talk by Prof de Magalhaes:
https://www.youtube.com/watch?v=GrLgYhtoBXA

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