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  Boosting fetal globin expression to treat inherited blood disorders


   School of Biotechnology and Biomolecular Sciences

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  Prof Merlin Crossley, Dr Kate Quinlan  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

UNSW is now accepting expression of interest for the next round of Scientia PhD Scholarships, including our project:

Boosting fetal globin expression to treat inherited blood disorders

These are exciting four-year scholarships to start in 2020 with full fees covered, a generous stipend, and career development funds.

Scheme URL: https://www.scientia.unsw.edu.au/scientia-phd-scholarships
Application closing date: 12 July 2019
Location: University of New South Wales, Sydney, Australia

PROJECT DESCRIPTION:
Mutations that affect the blood protein haemoglobin or its production are the most common single gene defects known. The individual and societal costs are enormous and disproportionately affect developing nations. Studies in human genetics have revealed that elevation of fetal globin effectively treats the disease. In this project we will use new CRISPR-gene editing technologies to investigate the regulation of the fetal globin gene and to boost fetal globin production.

IDEAL CANDIDATE:
The ideal candidate would be someone who has an interest and training in haematology and experience in molecular biology.

SUPERVISORY TEAM:
Prof Merlin Crossley – Science: Biotechnology & Biomolecular Sciences
Dr Kate Quinlan – Science: Biotechnology & Biomolecular Sciences
A/Prof Tracey O’Brien – Medicine: Women’s & Children’s Health

HOW TO APPLY:
Complete an expression of interest at: https://www.scientia.unsw.edu.au/scientia-phd-scholarships/boosting-fetal-globin-expression-treat-inherited-blood-disorders

The strongest expressions will receive an invitation to submit a full application to the scholarship competition.

About the School of Biotechnology and Biomolecular Sciences:
The School of Biotechnology and Biomolecular Sciences is one of the largest and most prestigious schools of scientific research and teaching in Australia. Research in the School ranges from human bacterial pathogens, hepatitis viruses, tissue engineering, cancer, cell biology, genetics and bioinformatics to functional genomics and extremophiles. Our staff have an international reputation for research excellence and have established collaborative links with industry and other research institutions in Australia and overseas.

About UNSW Sydney:
UNSW Sydney is a powerhouse of cutting-edge research, teaching and innovation. UNSW is one of the top 100 universities in the world, with more than 59,000 students and a 7,000-strong research community. Located in Sydney, Australia’s largest city, the University was established in 1949 with a unique focus on the scientific, technological and professional disciplines. UNSW is committed to making a difference by focusing on areas critical to the future. Pioneering research and sustained innovation are addressing some of the most important issues of today – from climate change and renewable energies to lifesaving medical treatments and breakthrough technologies. In the social sciences, UNSW research informs policy and expert commentary in issues facing society, ranging from human rights and constitutional recognition of Indigenous Australians to public health and population ageing. UNSW offers an extensive range of undergraduate, postgraduate and research programs.

CONTACT:
To discuss the project and related opportunities, please contact Merlin Crossley ([Email Address Removed]).

Funding Notes

The UNSW Scientia PhD Scholarship Scheme is part of our dedication to harnessing our cutting-edge research to solve complex problems and improve the lives of people in local and global communities. Scientia candidates will have a strong commitment to making a difference in the world with demonstrated potential for contributing to the social engagement and/or global impact pillars of the UNSW 2025 Strategy.
Applicants are required to express their interest in a specific research area with an identified supervisory team. There are over 190 research projects to choose from.