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Brain Tissue Pulsations: modelling and machine learning methods for the detection of raised intracranial pressure in adult intensive care

This project is no longer listed on and may not be available.

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  • Full or part time
    Dr E Chung
    Dr A Lecchini-Visintini
  • Application Deadline
    No more applications being accepted
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

Raised Intracranial Pressure (ICP) can occur in patients with bleeding or swelling of the brain in a number of brain pathologies such as head trauma, stroke, intracranial tumours and cerebral oedema. Raised ICP, if untreated, can lead to devastating brain damage. Prompt recognition and treatment is of paramount importance, but current monitoring methods require neurosurgical insertion of a device beneath the skull, which is extremely invasive.

This PhD project aims to develop criteria for the detection of raised ICP, based on non-invasive ultrasound measurements of brain tissue pulsations, for automated detection and monitoring of brain swelling. The methodology adopted in the project combines cerebral blood flow regulation modelling with machine learning methods. The project will support the development of a clinical ultrasound portable prototype being pioneered at Leicester, together with our industry partner (Nihon Kohden), for the rapid assessment of brain injury, and is expected to generate high impact biomedical engineering and clinical publications.

The ideal candidate will have a degree in Engineering, Physics, or Applied Mathematics and an interest in physiological modelling and machine learning methods.

Entry requirements:
You must hold (or be about to obtain) a First or an Upper Second Class UK undergraduate degree or an equivalent degree from a recognised EU institution, in an area relevant to the projects you are applying for.

Qualifications (or a combination of qualifications and experience) which demonstrate equivalent ability and attainment will also be considered. For example, a less than sufficient first degree may be enhanced to meet the requirements by the acquisition of a Distinction at Masters level or significant research experience gained from employment).

Informal enquiries:
If you have any questions or would like to find out more about IMPACT, please get in touch.
Email us at [Email Address Removed]

UK/EU applicants only

To apply:
please refer to

Funding Notes

The Studentship provides 3.5 years of Stipend at UKRI rates and Tuition fees at UK/EU rates

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