About the Project
O1. Identify antibiotic combinations that together select for evolution of antibiotic resistance even at low concentrations
O2. Employ genome sequencing to unravel key mechanisms underlying resistance evolution
O3. Re-evaluate current safe antibiotic discharge limits based on antibiotic resistance (O1) and global river sampling survey data of known antibiotic combinations and concentrations in global river network.
Experimental work will use a combination of in vitro microcosm experiments and genome sequencing to determine antibiotic resistance evolution of key clinical pathogens (P. aeruginosa, E. coli, S. aureus) under a range of antibiotic combinations in sublethal concentrations. The project will also build upon global river sampling survey that has determined the prevalence of antibiotics globally. An ideal candidate will have a background in at least one of the main subject areas (microbiology, experimental evolution, pathology, environmental chemistry) and willingness to develop skills in the other areas.
The Department of Biology at the University of York is committed to recruiting extraordinary future scientists regardless of age, ethnicity, gender, gender identity, disability, sexual orientation or career pathway to date. We understand that commitment and excellence can be shown in many ways and have built our recruitment process to reflect this. We welcome applicants from all backgrounds, particularly those underrepresented in science, who have curiosity, creativity and a drive to learn new skills.
Tax-free annual stipend at UKRI rate (£15,285 for 2020/21)
UK tuition fees (£4,473 for 2021/22)
Research support and training charges (RSTC)
Only UK students are eligible for this funding scheme.
A number of projects are competing for this funding scheme, each will nominate their strongest candidate to a Selection Panel. Nominated candidates will be invited for interview but only one student will be offered the studentship.
START DATE: 1st October 2021
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