About the Project
As part of the multidisciplinary Mesothelioma Research Programme at the University of Leicester http://www.mesothelioma-research-leicester.com/, we are recruiting patients and sampling multiple regions of their tumours.
This project will focus on the extensive copy number heterogeneity of mesothelioma, and its implications for the history of the tumour, prognosis and therapy. It can be developed along bioinformatic approaches, analysing data in an evolutionary context to analyse the nature and extent of copy number variation, or along more experimental biological approaches, using new long-read sequencing technologies to characterise genomic structural rearrangements in detail and to identify potential therapeutic targets,
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