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Cancer Research UK-funded studentship: Defining new targets for attenuating androgen receptor signalling in castrate-resistant prostate cancer

  • Full or part time
  • Application Deadline
    Wednesday, April 24, 2019
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

About This PhD Project

Project Description

Number of awards:

Start date and duration:
1 October 2019. Funding covers a four-year PhD.

Are you interested in investigating a key driver of advanced prostate cancer with a view to developing future therapeutics? Prostate cancer kills 12,000 men in the UK each year and requires new, more effective treatments. Aberrant androgen receptor activity drives fatal disease progression and represent a major clinical challenge. This project will identify tractable targets for inactivating androgen receptor signaling in contemporary models of advanced prostate cancer that will fill a critical knowledge gap in this field and provide new therapeutics for future patient treatment.
The successful applicant will undertake cross-disciplinary training in high-throughput screening platforms and bespoke molecular/cellular biology techniques within the Northern Institute for Cancer Research, Newcastle University, and be an integral member of a multi-disciplinary team involving molecular biologists, medicinal chemists and structural biologists together with both national and international collaborators.

For further information about this project please contact .

Cancer Research UK (

Name of supervisor(s):
Dr Luke Gaughan (, Mr Rakesh Heer, Professors Craig Robson and Steve Wedge, Northern Institute for Cancer Research (, Newcastle University (

Eligibility Criteria:
You must have, or expect to achieve, at least a 2:1 honour’s degree or international equivalent, in an appropriate subject, including: biochemistry, molecular biology or biomedical sciences. A further qualification such as an MRes is advantageous.

The award is available to UK/EU applicants only.

How to apply:
You must apply through the University’s online postgraduate application system. To do this please ‘Create a new account’ (
Only mandatory fields need to be completed. However, you will need to include the following information:

insert the programme code 8300F in the programme of study section
select ‘PhD in the Faculty of Medical Sciences – Cancer Research’ as the programme of study
insert the studentship code CR092 in the studentship/partnership reference field
attach a covering letter and CV. The covering letter must state the title of the studentship, quote the studentship reference code CR092 and state how your interests and experience relate to the project
attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications.

For further details, please contact:

Dr L Gaughan (
Northern Institute for Cancer Research (
Newcastle University (

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