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CardioSim: Experimental and Numerical Simulation of Cardiac Pathologies


School of Postgraduate Studies

Applications accepted all year round Funded PhD Project (Students Worldwide)

About the Project

The aim of this PhD project is develop novel experimental and computational models of cardiac pathologies.

Background: High-fidelity benchtop cardiac models enable efficient medical device testing, interventional training, and procedure demonstration. However, for left-heart simulators, the focus has been on valve hemodynamic competency and representative physiological left ventricular contraction. Existing test set-ups typically have fixed or non-contracting annular systems. This project will address an unmet clinical need to assess how valve annular dynamics affect structural integrity or hemodynamic ability in disease state conditions.

Combined with use of a high-fidelity finite element analysis cardiac model (Dassault Systemes Living Heart Human Model, 3ds.com/products-services/simulia/solutions/life-sciences/living-heart-human-model/), this project will involve the design a custom cardiac simulator capable of reproducing left heart annular dynamics for healthy and diseased valve configurations. This project will require image processing and reconstruction, 3D printing, flow rig design and finite element modelling to explore valvular mechanics.

For more information please contact Dr. Claire Conway ()

Applicant criteria:


Essential
• Minimum of an Upper Second-Class Honours (2.1) Bachelor’s degree, or equivalent, in Mechanical Engineering, Biomedical Engineering or related discipline.
• Excellent written and oral communication skills and a high level of competence in the English language.
• Ability to work independently, to take initiative and discuss/develop and communicate own ideas.

Desirable
• Previous experience in finite element analysis, image reconstruction, or 3D printing would be advantageous but not essential.

How to apply: Please apply via email to Dr. Claire Conway () with the subject heading “StAR PhD Project - CardioSim”. In your application include (in pdf format)
1. An up-to-date CV
2. A 500-word cover letter outlining your interest in and suitability for the position
3. Scanned transcripts (preferred), or detailed degree grade breakdown
4. Contact details of three referees

Positions will remain opened until filled but preferred start date is September 2020. Only short-listed applications will be acknowledged.

About the RCSI Tissue Engineering Research Group (TERG): TERG utilises biomaterials expertise to develop construct and living system technologies that can restore the structural and functional properties of damaged or degenerated tissues, whilst also trying to expand fundamental understanding in the fields of biomechanics and mechanobiology. TERG as a research centre and RCSI as a health sciences university, welcomes its responsibility to provide equal opportunities for all. We are actively seeking diversity in our research teams and particularly encourage applications from underrepresented groups.

For further information see: rcsi.com/dublin/research-and-innovation/research/research-centres-and-networks/tissue-engineering-research-group

Funding Notes

This position is funded by the RCSI – StAR Lectureship Programme (rcsi.com/dublin/research-and-innovation/research-careers/star-programme )

Successful candidates will receive stipend of €18,000 per annum (tax exempt) for 4 years plus registration fees (both EU and non-EU fees are supported in this scholarship).

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