Applications are invited for a PhD studentship to start in September 2019 in Dr Stellios Arseniyadis’ group at Queen Mary University of London (QMUL).
Background: The group is principally interested in developing new synthetic tools to attain high structural and functional complexity. These methods lie within the areas of organocatalysis, transition metal catalysis and, more recently, bio-hybrid catalysis. Although the applicability of these research topics can seem widespread, they’re all carried out with a common mindset: taking advantage of a unique reactivity pattern to tackle synthetic challenges with a special emphasis given to reactivity, selectivity and structural complexity. In this context, we’ve been particularly active in developing some highly enantioselective palladium-catalysed allylic alkylation processes . We’ve also been active in the field of DNA-based asymmetric catalysis trying to develop new synthetic transformations and applying them to the synthesis of natural products .
In the present project, we wish to develop new synthetic routes to highly enantio-enriched biaryl systems. The methods developed will be applied in the synthesis of new chiral catalysts as well as in the synthesis of various natural products.
Techniques and Training: Dr Arseniyadis’ group is based in the Joseph Priestley building which is fully equipped with state-of-the-art facilities, including high field NMR, EPR, AFM, IR and mass spectrometry, as well as HPLC and X-ray diffractometry. The successful student will receive complete training in a large number of organic chemistry techniques, in addition to developing transferable skills such as report writing, oral communication of results, project planning and organisation. All postgraduate researchers are part of the QMUL Doctoral College, which provides further high quality training in key skills such as critical thinking, teamwork and entrepreneurship. Candidates are expected to have a strong background and interest in synthetic organic chemistry. Prior experience in catalysis and multi-step synthesis is desirable but not required as the expertise of the group will provide an ideal training environment.
Environment: Queen Mary University of London is a member of the Russell group and is one of the leading research-focused institutions in the UK. All PhD students and post-doctoral researchers are part of the QMUL Doctoral College, which provides support with high-quality training and career development activities.
Eligibility and applying: Applications are welcome from outstanding students with or expecting to obtain a degree (equivalent to UK 1st or 2:1) in Chemistry. Previous experience with asymmetric organocatalysis or biocatalysis is desirable but not essential. Applicants from outside of the UK are required to provide evidence of their English language ability. Please see our English language requirements page for details: https://www.qmul.ac.uk/international-students/englishlanguagerequirements/postgraduateresearch/
For informal enquiries about the please contact Dr Arseniyadis and include your CV, a cover letter explaining eligibility and interest in the project and the contact details of two academic referees. Formal applications should be submitted online by the stated deadline.
For an overview of Dr Stellios Arseniyadis’ research, please visit his group website at https://arseniyadislab.sbcs.qmul.ac.uk
 (a) Aubert, S.; Katsina, T.; Arseniyadis, S. Org. Lett. 2019, 21, 2231. (b) Song, T.; Arseniyadis, S.; Cossy, J. Org. Lett. 2019, 21, 603. (c) Song, T.; Arseniyadis, S.; Cossy, J. Chem. Eur. J. 2018, 24, 8076. (d) Nascimento de Oliveira, M.; Arseniyadis, S.; Cossy, J. Chem. Eur. J. 2018, 24, 4810. (e) Nascimento de Oliveira, M.; Fournier, J.; Arseniyadis, S.; Cossy, J. Org. Lett. 2017, 19, 14. (f) Fournier, J.; Lozano, O.; Menozzi, C.; Arseniyadis, S.; Cossy, J. Angew. Chem. Int. Ed. 2013, 52, 1257. (g) Fournier, J.; Arseniyadis, S.; Cossy, J. Angew. Chem. Int. Ed. 2012, 51, 7562.
 (a) Mansot, J.; Aubert, S.; Duchemin, N.; Vasseur, J.-J.; Arseniyadis, S.; Smietana, M. Chem. Sci. 2019, 10, 2875. (b) Duchemin, N.; Skiredj, A.; Mansot, J.; Leblanc, K.; Vasseur, J.-J.; Beniddir, M. A.; Evanno, L.; Poupon, E.; Smietana,M.; Arseniyadis, S. Angew. Chem. Int. Ed. 2018, 57, 11786. (c) Duchemin, N.; Heath-Apostolopoulos, I.; Smietana, M.; Arseniyadis, S. Org. Biomol. Chem. 2017, 15, 7072. (d) Amirbekyan, K.; Duchemin, N.; Benedetti, E.; Joseph, R.; Colon, A.; Markarian, S. A.; Bethge, L.; Vonhoff, S.; Klussmann, S.; Cossy, J.; Vasseur, J.-J.; Arseniyadis, S.; Smietana, M. ACS Catal. 2016, 6, 3096. (e) Duchemin, N.; Benedetti, E.; Bethge, L.; Vonhoff, S.; Klussmann, S.; Vasseur, J.-J.; Cossy, J.; Smietana, M.; Arseniyadis, S. Chem. Commun. 2016, 52, 8604. (f) Benedetti, E.; Duchemin, N.; Bethge, L.; Vonhoff, S.; Klussmann, S.; Vasseur, J.-J.; Cossy, J.; Smietana, M.; Arseniyadis, S. Chem. Commun. 2015, 51, 6076. (g) Wang, J.; Benedetti, E.; Bethge, L.; Vonhoff, S.; Klussmann, S.; Vasseur, J.-J.; Cossy, J.; Smietana, M.; Arseniyadis, S. Angew. Chem. Int. Ed. 2013, 52, 11546.