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Cellular signalling networks regulation by tyrosine kinase receptors (RTK) in normal and cancer cells.

Project Description

The research team led by Professor Nicolas Bisson, Canada Research Chair in Cancer Proteomics, is studying signalling mechanisms that allow normal cells to coordinate a precise response to extracellular signals transmitted by RTK, and the deregulation of these mechanisms in cancer cells. The team is particularly interested by signalling networks that are dependent on RTK activation. Advanced techniques in molecular and cellular biology, biochemistry and proteomics are utilized (Bisson et al., Nature Biotechnology 2011; Beigbeder et al., Scientific Reports 2017; Banerjee et al., Journal of Proteomics 2018; Jacquet et al., Molecular and Cellular Proteomics 2018; Dionne et al., Molecular Cell 2018.

The lab is located within the Centre de recherche du CHU de Québec-Université Laval (Hotel-Dieu of Quebec campus), a modern facility located in historic Old Quebec City, Canada ( The institute houses more than thirty teams active in fundamental and clinical research in oncology (

We are looking for dynamic, motivated and rigorous graduate students - PhD candidates. Selected individuals will be in charge of an independent project and will benefit from training adapted to their career goals. Requirements: academic training in biology, biochemistry, microbiology or equivalent; enrolment in a graduate program of U. Laval for Fall 2019 (September) or Winter 2020 (January).

Interested candidates must submit the following documents to the specified e-mail address, grouped into a single PDF document, for their application to be considered:
- Personalized motivation letter indicating research interests and career plans;
- Up-to-date CV, including the name and contact information of 3 references;
- Scans of official transcripts/unofficial transcripts.
Only selected candidates will be contacted.

Funding Notes

Funding is available for the project and for student salaries until 2024. Selected candidates will be expected to apply for studentships.


Please provide the the name and contact information of 3 references in CV.

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