University of Birmingham Featured PhD Programmes
National University of Ireland, Galway Featured PhD Programmes
King’s College London Featured PhD Programmes
University of Kent Featured PhD Programmes
University of Manchester Featured PhD Programmes

Characterisation vascular function in ischemic heart disease


Project Description

The use of the left internal mammary artery (LIMA) to bypass the left anterior descending artery (LAD) is the “gold standard” for coronary artery bypass grafting. We wish to examine whether the layer of fat around the artery can affect the outcome of bypass, due to the complex milieu of adipokines and cytokines it secretes. This is important clinical investigation due to the obesity epidemic and its association with increased incidence and mortality in many diseases.

This project will seek to

1. Characterise internal mammary artery function in obese/non-obese patients undergoing CABG in relation to adipokine profile and adipose tissue inflammatory status

2. Correlate IMA function, adipokine profile and adipose tissue inflammatory status with successful, infection free coronary artery bypass grafting (CABG). Identify potential circulating biomarkers which are associated with successful outcome to inform best graft choice (IMA or saphenous vein) to achieve successful CABG


Further details:
This is a collaborative, translational project with Nidal Bittar at Blackpool Hospital using patient samples.

Funding Notes

This PhD is self-funded.

We welcome applications from Home/EU and Overseas self-funded students and those seeking their own funding from external sources who meet the entry requirements and are able to cover all the costs, including tuition fees, research costs and living expenses

Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here
* required field
Send a copy to me for my own records.

Your enquiry has been emailed successfully





FindAPhD. Copyright 2005-2019
All rights reserved.