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About the Project
The molecular mechanisms that regulate receptors and receptor are complex and are often studied in two-dimensional cell culture systems. However, there is growing evidence that cells react and respond differently in three-dimensional culture. Our work is particularly focused on cell-surface receptors and ion channels. We will explore the differences in receptor trafficking and signaling in two- and three-dimensional cultures and how this affects biological outcomes.
Studies will provide will provide specialist training in molecular, biochemical, pharmacological, microscopic and genetic tools to discover new targets for the treatment of many human disorders including migraine, asthma and inflammatory bowel disease.
Funding Notes
Students with their own financial support are welcome to contact at anytime.
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