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China Scholarship Council: Non-lysine ubiquitination in health and disease

  • Full or part time

    Dr Gopal Sapkota
  • Application Deadline
    Wednesday, January 15, 2020
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

The School of Life Sciences at the University of Dundee, joint with the China Scholarship Council (CSC), is proud to be able to offer a scholarship programme for postgraduate research students. The scholarship covers all tuition fees and research fees and provides living expenses and one return flight ticket to successful candidates. There are up to 5 scholarships of 4 years duration available.

Ubiquitination is a posttranslational modification that regulates all aspects of physiology and aberrant ubiquitination has been implicated with numerous diseases. Ubiquitination is typically considered a posttranslational modification of lysine residues but it is emerging that non-lysine ubiquitination is intrinsic to mammalian biology. This project will use a multidisciplinary approach to understand the cellular function of non-lysine ubiquitination. This will involve the identification of ubiquitin system enzymes that carry out non-lysine ubiquitination and identification of atypical sites within substrate proteins.

The project will provide experience with a range of techniques such as cell biology, proteomics and structural biology. Inquisitive and technically minded applicants should find the lab a stimulating environment to conduct research.

1. Pao et al., Nature Chemical Biology 2016, 12 (5), 324.
2. Pao et al., Nature 2018, 556 (7701), 381.

Funding Notes

In order to be eligible for these awards applicants must:

Be a Chinese national
Meet the requirements of the CSC – please see their website
Hold an unconditional offer to study for a PhD at the University of Dundee and meet our English language requirements
Have completed bachelors or masters degree before the agreed start of PhD study.

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