We are seeking a motivated candidate to examine how translation of specific mRNAs is controlled in dinoflagellates. A background in biochemistry/cell or molecular biology is required, and knowledge of bioinformatics is an asset. Candidates with an interest in marine biology are encouraged to apply.
The PhD project will investigate the mechanisms regulating translation of specific mRNAs in dinoflagellates. Translation of specific mRNAs is correlated with several known daily rhythms, such as photosynthesis, cell cycle and bioluminescence. Understanding how translation of specific RNAs is controlled is thus key to understanding how cells change their biochemistry to specialize for different tasks at different times of day. The initial focus will be on examining the RNA-protein interactome at different times over the daily period.
Please send your candidature to [Email Address Removed] complete with: a motivation letter and research interests (1 page max), CV, grade records and email addresses of 2 referees. The position is open immediately and will remain open until filled.
Selected reading
Label-free MS/MS analyses of the dinoflagellate Lingulodinium identifies rhythmic proteins facilitating adaptation to a diurnal LD cycle
C Bowazolo, PK Sirius, M Beauchemin, SCL Lo, J Rivoal, D Morse
Science of The Total Environment 704, 135430
Translation and translational control in Dinoflagellates
S Roy, R Jagus, D Morse
Microorganisms 6 (2), 30
miRNAs Do Not Regulate Circadian Protein Synthesis in the Dinoflagellate Lingulodinium polyedrum
S Dagenais-Bellefeuille, M Beauchemin, D Morse
PloS one 12 (1), e0168817
The Symbiodinium kawagutii genome illuminates dinoflagellate gene expression and coral symbiosis
S Lin, S Cheng, B Song, X Zhong, X Lin, W Li, L Li, Y Zhang, H Zhang, Z Ji, ...
Science 350 (6261), 691-694
Key words: Montreal, Canada, Biochemistry, Cell Biology, Circadian rhythm, Dinoflagellate, Translation
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