About the Project
https://www2.mrc-lmb.cam.ac.uk/group-leaders/T-to-Z/marco-tripodi/
We study the organization and function of neural circuits controlling goal-oriented movements in mice.
The project will focus on understanding how animals produce an accurate body-bound map of the surrounding space that can be used to direct targeted movements and which neuronal populations are directly involved in identifying salient positions on such a map.
In order to answer these questions the candidate will use a combination of novel viral approaches, mouse genetics, electrophysiology, in vivo multiphoton and lightsheet microscopy and behaviour in virtual reality environments.
References
Kristopher T. Jensen, Ta-Chu Kao, Marco Tripodi and Guillaume Hennequin. Manifold GPLVMs for discovering non-Euclidean latent structure in neural data. Jun 2020, arXiv:2006.07429
Laura Masullo, Letizia Mariotti, Nicolas Alexandre, Paula Freire-Pritchett, Jerome Boulanger and Marco Tripodi. Genetically defined functional modules for spatial orienting in the mouse superior colliculus. Current Biology, 2019, Sept 9; 29(17): 2892-2904
Jonathan J. Wilson, Nicolas Alexandre, Caterina Trentin and Marco Tripodi. Three-dimensional representation of motor space in the mouse superior colliculus. Current Biology, 2018 June 4; 28, 1-12
Ernesto Ciabatti, Ana González-Rueda, Letizia Mariotti, Fabio Morgese and Marco Tripodi. Life-long genetic and functional access to neural circuits using Self-inactivating Rabies virus. Cell, 2017 Jul 13;170(2):382-392
