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Combining omega-3 docosahexaenoic acid and melatonin to manage spinal cord injury-induced central neuropathic pain.


Project Description

About half of spinal injury patients develop neuropathic pain, which is driven by neuroinflammation, has no effective treatments, and impacts significantly on daily functioning. This project aims to develop a novel synergistic treatment combining omega-3 docosahexaenoic acid and melatonin in order to prevent/treat this pain. The student will gain expertise in pre-clinical research and a range of laboratory assay techniques. He or she will join an established group which is actively working on projects investigating treatments for pain which can be rolled out to human studies in future.

APPLICATION PROCEDURE:
Formal applications can be completed online: https://www.abdn.ac.uk/pgap/login.php. You should apply for Degree of Doctor of Philosophy in Medical Sciences, to ensure that your application is passed to the correct person for processing.

NOTE CLEARLY THE NAME OF THE SUPERVISOR AND EXACT PROJECT TITLE ON THE APPLICATION FORM.

Funding Notes

This is a 3-year PhD studentship fully funded by NIAA and is available to UK/EU students only. The stipend rate is set at current MRC rates. The Consumable budget is around £10K p.a.

Candidates should have (or expect to achieve) a minimum of a First-Class Honours degree in a relevant subject. Applicants with a minimum of a 2:1 Honours degree may be considered provided they have a Commendation or Distinction at Masters level. Previous lab experience in neuronal and glial cell cultures as well as ex vivo model of spinal cord injury is desirable.

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