The working and social climate for the majority of people in UK has changed dramatically in recent months. Adapting to online working and socializing has added to the sources of potential stress in our lives. An inability to handle stress – which is often exacerbated by adverse childhood experiences – is a key predictor of problems with mood and cognition, such as memory and decision-making. In this project the student will examine key differences between psychosocial stressors experienced in person, to those experienced online. We will also examine how differences in this stress reactivity relates to levels of GABA, the primary inhibitory neurotransmitter, within critical brain regions linked to stress.
First, the student will carry out behavioural studies to examine how people respond to an online stress task, compared to a stress task carried out face to face. They will then examine whether people with a history of early life stress differ in their responses to this social stress. Last, they will carry out a Magnetic Resonance Spectroscopy study to test whether levels of GABA in the anterior cingulate cortex differ between those who are highly stress-reactive, compared to those who are more resilient.
Throughout the project the student will have the opportunity to work in a thriving academic environment with opportunities to expand their PhD studies throughout.
Candidates are expected to hold (or be about to obtain) a minimum upper second class honours degree (or equivalent) in a related area/subject. Candidates with previous laboratory experience are particularly encouraged to apply.
How To Apply
For information on how to apply for this project, please visit the Faculty of Biology, Medicine and Health Doctoral Academy website (https://www.bmh.manchester.ac.uk/study/research/apply/). Informal enquiries may be made directly to the primary supervisor. On the online application form select the appropriate subject title.
For international students, we also offer a unique 4 year PhD programme that gives you the opportunity to undertake an accredited Teaching Certificate whilst carrying out an independent research project across a range of biological, medical and health sciences.
Equality, Diversity and Inclusion
Equality, diversity and inclusion is fundamental to the success of The University of Manchester, and is at the heart of all of our activities. The full Equality, diversity and inclusion statement can be found on the website https://www.bmh.manchester.ac.uk/study/research/apply/equality-diversity-inclusion/”