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Computational approaches to mining the rumen microbiome for novel antimicrobials.


   Institute of Biological, Environmental and Rural Sciences (IBERS)

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  Dr C Creevey  No more applications being accepted  Funded PhD Project (European/UK Students Only)

About the Project

A PhD fellowship funded through the Life Sciences Research Network, Wales is available to work on an inter-institutional project between the Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University and the School of Biological Sciences, Bangor University. The project will involve the computational and functional genomics investigation of natural microbial communities, such as in the Rumen, for novel antimicrobial agents.

Background: The alarming increase in antibiotic resistance in pathogenic bacteria, coupled with the decrease in drug discovery rates, is now a serious medical challenge that requires novel approaches to identify new novel therapeutic compounds such as antimicrobial peptides (AMPs). Generally, AMPs are produced by microbes in response to competitive stress for limited resources and our team in the Institute of Biological, Environment and Rural Sciences (IBERS) at Aberystwyth University have led the field in identifying AMPs from natural anaerobic environments, such as the rumen of cattle. We now have an exciting Ph.D. studentship opportunity for an ambitious candidate to join our team to develop novel computational approaches to identifying AMPs from metagenomic sequencing data to compliment our on-going work.

Contact Dr. Chris Creevey ([Email Address Removed]) to discuss the project, or for general queries IBERS Postgraduate Co-ordinator Michelle Allen ([Email Address Removed]). For funding reasons, this position is only open to UK/EU candidates. For information on the project visit http://www.aber.ac.uk/en/ibers/ibers-pg-study/postgraduate-research-opportunities/ and for how to apply see http://www.aber.ac.uk/en/postgrad/howtoapply/ - please enter the lead supervisor name (Chris Creevey) under “Computational approaches to mining the rumen micro biome for novel antimicrobials”.



Funding Notes

Ideal candidates: The fully funded 3-year PhD scholarship pays university postgraduate tuition fees (currently £4,052pa) and a stipend of £14,057 tax free per year. Applicants should hold, or expect to obtain, a minimum of a first or upper-second class honours degree (or equivalent) in a relevant subject (e.g. Molecular Biology, Bioinformatics, Computer Science).

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