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Continuous monitoring of acquired resistance to targeted therapy using circulating small RNA sequences( Ref: WD_2022_14_WSCH)


   Research Support Unit

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  Dr S Rani, Dr E McNeela, Dr O O'Donovan  No more applications being accepted  Funded PhD Project (Students Worldwide)

About the Project

Post summary

Applications are invited for a PhD position funded by WIT Presidents PhD Scholarship Programme.

The work will involve working in areas of Cancer Biology. The ideal candidate would be someone with expertise in Molecular Biology and Bioinformatics. The work will involve working with High Throughput OMICS datasets such as Next Generation Sequencing and Proteomics datasets. The successful applicant will also be required to work with Cancer Cell Lines and Clinical Samples. Expertise in Cell and Molecular Biology and Bioinformatics will be highly desirable.

The aim of the project is to actively monitor acquired drug resistance from Clinical samples and develop a drug resistance model in Cell Lines. Genomic profiling will be performed on Clinical samples and Cell lines to identify biomarkers for acquired resistance. 

Person specification

Qualifications

Essential

·       The successful candidate must have BSc degree in bioinformatics, molecular biology, biomedical science or related discipline

Desirable

·           MSc degree in bioinformatics, molecular biology, biomedical or related discipline

Knowledge & Experience

Essential

·       Molecular Biology

·       Bioinformatics

Desirable

·       Laboratory techniques such as Cell Culture, RNA isolation, qPCR.

·       Next Generation Sequencing and OMICS data analysis.

·       Programming skills R or Python.

·       Excellent written and communication skills.

Skills & Competencies

Essential

·       Applicants whose first language is not English must submit evidence of competency in English, please see WIT’s English Language Requirements for details.

·       Well organised, planning, and organisational skills

·       Good spoken English and communication skills

·       Proactive, enthusiastic, motivated, flexible, and problem-solving attitude

·       Able to work independently and as a member of a team

·       Good computer/IT skills

Desirable

·       Scientific writing (in English) skills


Funding Notes

Supervisor(s) : Dr Sweta Rani (WIT), Dr. Jai Prakash Mehta (ITC), Dr. Edel A. McNeela (WIT), Dr. Orla O'Donovan (WIT)
Research Group :Pharmaceutical and Molecular Biotechnology Research Centre (PMBRC)
Department / School:Department of Science
Duration: 4 years
Status: Full-time Structured PhD Programme
Funding information: WIT Presidents PhD Scholarship Programme
Value of the scholarship per year for four years
Stipend: €15,000
Fees: €4,500
Research Costs: €2,000
Teaching requirement : 168 hours of academic development activities over the 4-year term of the PhD programme in line with scholarship requirements.
Closing date and time: 23rd May 2022 at4PM Irish time
Interview date: TBC
Commencement date : September 2022

References

Further information
For any informal queries, please contact Dr. Sweta Rani at email: srani@wit.ie or telephone: +00353 (0) 51 842472
For queries relating to the application and admission process please contact the Postgraduate Admissions Office via email rpgadmissions@wit.ie or telephone +353 (0)51 302883.
Website: www.wit.ie
Application procedure
Download the Research Postgraduate Application Form and return completed applications to rpgadmissions@wit.ie, quoting (RSU to provide) in the email subject line. Please note that paper submissions will not be accepted
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