Control of cellular differentiation in the developing brain

An exciting opportunity exists to join our laboratory to investigate fundamental processes that regulate the development of the brain. This project aims to understand how mature brain cells form during foetal life. The central hypothesis is that a specific transcription factor family, called NFI, regulates the epigenetic state of the cell to control cellular differentiation. Methods used involve epigenomic and transcriptomic analyses of cells isolated from transgenic mouse models and the translation of this work to understanding the aetiology of human developmental brain disorders. In the long term, the results could also have broad impacts in the areas of stem cell and cancer biology, and in understanding mechanisms of brain formation that promote normal cognitive development. Our laboratory has extensive international networks and collaborations related to this work as well as a distinguished record of training highly successful scientists.

Preferred educational backgrounds include, but are not limited to:
Bachelor of Science or Biomedical Science with Honours or a Masters degree in a relevant discipline. Candidates with a background and relevant laboratory experience in molecular biology, especially in RNA-seq, ChIP-seq or ATAC-seq are preferred.

Informal inquiries can be made to Professor Linda Richards AO PhD ([Email Address Removed]) with a copy of your curriculum vitae, academic transcripts and cover letter.