About the Project
Medical Biophysics at the Institute of Physiology and Pathophysiology, Heidelberg University
Ph.D. position: Corticothalamic interactions in perceptual salience
We are seeking a highly motivated and technically oriented Ph.D. student to study neuronal circuit mechanisms underlying sensory learning and salience encoding in the thalamocortical system. The project combines behavior (texture discrimination in freely moving mice), optogenetics/chemogenetics and electrophysiology.
Key words for methods that will be used:
electrophysiology, optogenetics, in vivo, behavior, mathematical/computational modeling, cognition, learning
A Diploma/Masters in a biomedical, life-science or related discipline (e.g. neuroscience, biology, medicine, physics, cognitive science). Experimental experiences in neurosciences are a prerequisite (preferably neurophysiology and / or behavior). Experience in data analysis or programming using MATLAB/Python/R etc. is strongly preferred. Experience in methods to obtain and interpret neurophysiological data, and /or behavioral assays is highly desirable. Applicants with strong analytical skills and a flair for handling large datasets are particularly encouraged to apply. The working language in the lab is English.
The application in a single pdf should include: A cover letter with a brief personal research statement, specific research interests and career goals (max 1-2 pages), two letters of recommendation, CV, academic transcripts
The desired start for the Ph.D. project is within the first quarter of 2021.
Direct application link through HBIGS PhD program
• Corticothalamic spike transfer via the L5B-POm pathway in vivo. R.A. Mease, A. Sumser, B. Sakmann and A. Groh. Cerebral Cortex. (2016).
• Cortical control of adaptation and sensory relay mode in the thalamus. R.A. Mease, P. Krieger and A. Groh. Proceedings of the National Academy of Sciences USA. (2014).
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