Customised Drug Release by Additive Manufacturing
To apply personalised medicine, as a customization of health care to individual patients, through linking personal diagnostics, can increase the effectiveness of the prescribed treatment regimen and to minimise their adverse effects. However, the limitations of the traditional formulation can hardly achieve the complex drug release functions.
The 3D printing offers the potential for the manufacture of bespoke solid oral dosage forms, which enable the creation of activate pharmaceutical ingredient formulations with programming releasing functions, where the dose & the matrix to release when and where it is needed. 3D printing (particularly ink jet, extrusion, hot melt extrusion) of drug(s), offer the possibility of reducing the number of manufacturing steps as currently used in traditional tablet production process.
This project “formulation for programming releasing” aims to develop multi-material structures embedded with drugs, allowing a controlled drug release. The main objectives of the project are to 1) simulate and design the functional structure, 2) to develop the 3D printing system for the manufacturing of the structure and 3) to evaluate the design.
The ideal student would have an interest in the medical application of additive manufacturing and possess strong mechanical skills and (bio) separation and interdisciplinary technologies.
This is an open call for candidates who are sponsored or who have their own funding. If you do not have funding, you may still apply, however Institutional funding is not guaranteed. Outstanding candidates (UK/EU/International) without funding will be considered for any funding opportunity which may become available in the School.
Find out more: http://www.lboro.ac.uk/research/amrg/
Entry requirements Applicants should have, or expect to achieve, at least a 2:1 Honours degree (or equivalent) in Mechanical Engineering, Chemical Engineering, Chemistry or a related subject.
A relevant Master’s degree and/or experience in one or more of the following will be an advantage: Additive Manufacturing or Pharmaceuticals, Chemical engineering and Chemistry.
How to apply: All applications should be made online at http://www.lboro.ac.uk/study/apply/research/. Under programme name, select Mechanical & Manufacturing Engineering
Please quote reference number: XH2UF2018
The 2018 fees are as attached UK/EU: £4,195, International: £20.500
The 2019 fees are UK/EU: £TBC, International: £21,100