De novo synthekines for treatment of autoimmune diseases
Inflammation is essential for responding to infection and tissue damage. Its dysregulation, however, causes autoimmune diseases and chronic inflammation. Modulating cytokine activity has emerged as an important therapy for autoimmune conditions such as rheumatoid arthritis and uveitis. In this project you will computationally design new-to-nature proteins that mimic cytokines and test their therapeutic potential in autoimmunity
This chemistry project is a competitively funded PhD as part of the GW4 BioMed2 MRC DTP, with a start date of October 2023 as part of the research theme Infection, Immunity, Antimicrobial Resistance and Repair INFECTION, IMMUNITY, ANTIMICROBIAL RESISTANCE AND REPAIR – GW4 Biomed
About the GW4 BioMed2 Doctoral Training Partnership
The partnership brings together the Universities of Bath, Bristol, Cardiff (lead) and Exeter to develop the next generation of biomedical researchers. Students will have access to the combined research strengths, training expertise and resources of the four research-intensive universities, with opportunities to participate in interdisciplinary and 'team science'. The DTP already has over 90 studentships over 6 cohorts in its first phase, along with 20 students in its second phase.
Deadline: 5pm, Wednesday 2nd November 2022.
If you are shortlisted for interview, you will be notified by Friday 16th December 2022. Interviews will be held virtually on 25th and 26th January 2023.
Eligibility
Residency: The GW4 BioMed2 MRC DTP studentships are available to UK and International applicants. The UKRI now classifies EU students as international unless they have rights under the EU Settlement Scheme. The GW4 partners have all agreed to cover the difference in costs between home and international tuition fees. This means that international candidates will not be expected to cover this cost and will be fully funded but need to be aware that they will be required to cover the cost of their student visa, healthcare surcharge and other costs of moving to the UK to do a PhD. All studentships will be competitively awarded and there is a limit to the number of International students that we can accept into our programme (up to 30% cap across our partners per annum).
Academic criteria: Applicants for a studentship must have obtained, or be about to obtain, a UK degree, or the equivalent qualification gained outside the UK, in an appropriate area of medical sciences, computing, mathematics or the physical sciences. Academic qualifications are considered alongside significant relevant non-academic experience.
English requirements: If English is not your first language that you must fulfil our English Language criteria before the start of your studies. Details of accepted English Language qualifications for admissions can be found here https://www.cardiff.ac.uk/study/international/english-language-requirements/postgraduate
How to Apply
Please complete an application to the GW4 BioMed2 MRC DTP on their website - How to Apply for Students – GW4 Biomed
Further Information
For informal enquiries, please contact [Email Address Removed]
Applicants interested in the project are strongly recommended before applying, to contact Dr Rhys for a chat [Email Address Removed]
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