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Design and realisation of nanomedicine using computer simulation and smart nanofracturing method

School of Pharmacy

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Dr Y Tian Applications accepted all year round Self-Funded PhD Students Only

About the Project

Nanomedicine is the application of nanotechnology in healthcare sector, for the diagnosis, monitoring, prevention and treatment of many unmet clinical conditions. The promises of nanomedicine for the revolution of healthcare is far reaching with a projected market value of $200 Billion by 2020. Specific efforts have been focused on drugs that are difficult to deliver due to low water solubility and high toxicity. Further development of structurally-engineered nanocarriers capable of delivery drugs to targeted disease cells and tissues is also another area with tremendous potential. However, manufacturing nanomedicine is very challenging because of their particle size and complex formulation. Significant issues with reproducibility and scalability have been causing high failure rates in translating nanomedicine from bench to the clinic. Here we have developed a highly interdisciplinary project in collaboration with DIMENSION group at Warwick University to improve the design and realisation of liposome based nanomedicine. This approach will enable us to identify the best liposome design for a given drug, as well as promote the realisation of the nanomedicine via smart nanofracturing method.

Funding Notes

Applicants should have a 1st or 2.1 honours degree (or equivalent) in a relevant subject. Relevant subjects include Pharmacy, Molecular Biology, Pharmaceutical Sciences, Biochemistry, Biological/Biomedical Sciences, Chemistry, Engineering, or a closely related discipline. Students who have a 2.2 honours degree and a Master’s degree may also be considered, but the School reserves the right to shortlist for interview only those applicants who have demonstrated high academic attainment to date
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