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There is huge scope to replicate the complex nature of tissue, through the design and additive manufacturing (AM) of biomaterials. In nature, interfaces between tissues generally demonstrate a grading effect in terms of composition and mechanical function for example the osteochondral junction. Synthetic materials are made with a homogenous composition and then bonded together. AM offers the ability to change key parameters of a structure throughout manufacturing, which can enable functional grading by varying the geometry or materials or both. This can be achieved through different methods; the percent composition of raw materials, process parameters, or geometric variations such as lattices. Whilst functional grading can be achieved through AM, the design and computational validation of functionally graded structures poses a significant challenge.
The aim of this research project is to create a methodology to enable the design and/or validation of functionally graded materials. This project will utilise a sub-zero bioprinter to explore the functional grading of extruded biomaterials, and the capacity to change the material and mechanical properties throughout the specimen. Ideally, the project will require the applicant to be confident in laboratory skills and/or computational skills. However, the project may be tailored to a strong laboratory or a strong computational/mathematical skill set. Applicants with either strong laboratory or computational skills, with an enthusiasm to learn the foundations of the other discipline, are encouraged to apply.
Person Specification
Essential:
• A first-class degree in a relevant discipline (Engineering (Mechanical or Chemical), Material Sciences, Physics, Applied Mathematics)
• To have met the University of Birmingham English Language requirements (e.g. IELTS 6.0 with no less than 5.5 in any band) by the point of application.
Desirable:
• Good knowledge of engineering, design, mechanics and materials
• Experience in performing experimental work, collecting data and analysing research findings
• Experience in performing computational work (e.g. ABAQUS or MATLAB)
• Experience in CAD software packages (e.g. Fusion 360)
How to apply
Eligible applicants should first send an expression of interest to Dr Lauren Thomas-Seale ([Email Address Removed]), including the following:
• 200 words cover letter on how your experience, qualifications and research interest aligns with this position
• CV including your academic and work experience with the names of two referees.
We value diversity and inclusion at the University of Birmingham and welcome applications from all sections of the community. The Thomas-Seale group is founded on the principle of inclusivity in research, should applicants have any enquiries about how to conduct a PhD with reasonable adjustments for a protected characteristic, they are encouraged to contact the Dr Thomas-Seale.
Funding notes:
Applicants are required to send an expression of interest (as detailed above) to Dr Lauren Thomas-Seale ([Email Address Removed]). Short-listed applicants, will be invited to an interview with the supervision team. After the interview, the successful candidate will be invited to apply through the University of Birmingham website (https://sits.bham.ac.uk/lpages/EPS013.htm).
School of Engineering funding is available, through a competitive application. This funding will cover tuition fees and provide a stipend for 3.5 years. Self-funded students are also welcome to apply.
Research output data provided by the Research Excellence Framework (REF)
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