Developing a class of self-immolitive near-infrared (NIR) responsive polymers for triggered drug delivery
The use of polymers for drug delivery is a well-established field. Typically drugs are loaded into polymer micelles, vesicles or hydrogels and passively released overtime. This method of delivery is effective but lacks the ability to be triggered using external stimuli. Triggered drug delivery systems can be used for targeted delivery at specific locations or on-demand delivery.
During the course of this project you will develop a class of near-infrared (NIR) responsive polymers that de-polymerise in response to irradiation with NIR light. Similar to systems that are used in lithography. Specifically once developed these polymers will be used as drug delivery polymers in a number of forms and the triggered drug release will be studied.
Due to the multidisciplinary nature of this project, students from a variety of backgrounds are welcomed. The successful candidate will have experience with polymer synthesis and characterisation and/or experience of working with NIR responsive groups. You will be a trustworthy, conscientious, independent experimental scientist who is able to work as part of a larger team.