Don't miss our weekly PhD newsletter | Sign up now Don't miss our weekly PhD newsletter | Sign up now

  Developing an intervention to increase the receipt of oral cancer screening amongst adults with severe mental illness (SMI)


   Institute of Dentistry

This project is no longer listed on FindAPhD.com and may not be available.

Click here to search FindAPhD.com for PhD studentship opportunities
  Dr A Tappuni, Dr Easter Joury  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

Background:

There are stark health inequalities between people with severe mental illness (SMI) and the general population.1 SMI is a mental illness (such as schizophrenia, bipolar disorder or other related psychotic disorders) that results in substantial functional impairment. Individuals with SMI die decades earlier when compared to the general public.2 Most of this inequality in mortality is related to preventable and treatable chronic conditions, such as cancer.3

Mental illness is associated with higher levels of cancer risk factors such as obesity, smoking, drinking alcohol and poor diet.4 People with SMI who develop cancer had higher mortality rate than those in the general population with cancer.3 This could be explained by the late detection and lower rate of uptake of cancer screening amongst this disadvantaged group of the population.3

The incidence and mortality rates of oral cancer is rising.5-7 Most cases present late, which reduces prognosis.8 This is more likely to occur amongst people with SMI given the fact that disadvantaged groups bear the greatest share of the oral cancer burden.

Oral cancer should be amenable to early detection, diagnosis and treatment due to its location and easy access.8 This in turn can improve survival outcomes, and reduce therefore inequalities experienced by people with SMI. Primary care practitioners, in dental and medical settings, have a key role in the early diagnosis of oral malignancy.8-11 Given the low rate of cancer screening uptake amongst people with SMI, there is a need for an intervention to increase oral cancer screening amongst this disadvantaged group. This in turn requires a better understanding of the multiple barriers and facilitators to receiving oral cancer screening from the perspectives of different stakeholders, especially the service users. Currently, very little is known regarding such barriers and facilitators.

Aims:

This study is a mixed method and trans-disciplinary (dentistry, psychiatry and public health) study that will be conducted in three stages. It aims to inform a co-produced, theory-based, multilevel interventions to increase oral cancer screening amongst people with SMI, through:

·      Exploring the views, experiences and suggestions of adults with SMI, their carers, mental health and dental care teams, and commissioners regarding the multilevel barriers and facilitators to the receipt of oral cancer screening amongst adults with SMI (Stage 1),

·      Prioritising the facilitators identified in Stage 1 and formulate consensus (Stage 2), and

·      Developing a logic model (theory of change) to explain how prioritised facilitators identified in Stage 2 could lead to an increase in the receipt of oral cancer screening amongst adults with SMI (Stage 3).Applicants need BDS or equivalent or a good health related first or public health, health psychology or behavioural science degree (minimum of a 2:1) and a relevant Master’s degree or an equivalent professional qualification.



Funding Notes

We will consider applications from prospective students with a source of funding to cover tuition fees and bench fees for three years full-time or 6 years part-time. Both self-funded and sponsored students will be considered.

References

1. Public Health England. Severe mental illness (SMI) and physical health
inequalities: briefing, 2018. Available at: https://www.gov.uk/government/publications/severe-mental-illness-smi-physical-health-inequalities/severe-mental-illness-and-physical-health-inequalities-briefing
2. Walker ER, McGee RE, Druss BG. Mortality in mental disorders and global disease burden implications: a systematic review and meta-analysis. JAMA Psychiatry 2015, 72:334-341.
3. Weinstein L, Stefancic A, Cunningham A, Hurley K, Cabassa L, Wender R. Cancer prevention, screening, and treatment in people with mental illness. CA: A cancer journal for clinicians. 2016;66(2):133–51.
4. Kisely S, Crowe E, Lawrence D. Cancer-related mortality in people with mental illness. JAMA psychiatry. 2013; 70(2):209–17.
5. Conway DI, Stockton DL, Warnakulasuriya KAAS, Ogden G, Macpherson LM. Incidence of oral and oropharyngeal cancer in United Kingdom (1990-1999) – recent trends and regional variation. Oral Oncol 2006;42:586-92.
6. Cancer Research UK. Oral Cancer Statistics. Available at: www.cancerresearchuk.org/cancerinfo/ cancerstats/keyfacts/oral cancer
7. Public Health England. Oral Cancer in England. A report on incidence, survival and mortality rates of oral cancer in England, 2012 to 2016. Available at: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/891699/Oral_cancer_report_170420.pdf
8. Farnaras N, Warnakulauriya S. Oral cancer diagnosis in primary care. Prim Dent J. 2016; 5(5): 64-68.
9. Ford PJ, Farah CS. Early detection and diagnosis of oral cancer. Journal of Cancer Policy. 1 (2013) e2-e7.
10. Wade J, Smith H, Hankins M,Llewellyn C. Conducting oral examinations for cancer in general practice: what are the barriers? Fam Pract. 2010 Feb;27(1):77-84.

11. Oral Health Foundation The State of Mouth Cancer UK Report 2020/21; 2021. Available at: https://www.dentalhealth.org/Handlers/Download.ashx?IDMF=08b28d55-f52f-4b21-a9a0-342d041c5d0c
12. De Meeyrick, J. The Delphi method and health research. Health education. 2003; 103(1), 7-16.