We are a clinical and experimental lab at the MRC London Institute of Medical Sciences & Imperial College London. Our research investigates new mechanisms and treatments for human obesity and diabetes using high-throughput molecular screening in patients and targeted hypothesis testing in experimental systems.
The project will study how weight loss brings about ‘cure’ of type 2 diabetes, and whether this response can be mimicked with pharmacotherapies. It is a collaborative project with Professor Molly Stevens’ lab in the Department of Bioengineering. Together, we aim to (i) identify and characterise exosomes (extracellular vesicles secreted by cells that contain bioactive molecules) involved in the reversal of diabetes pathophysiology after human weight loss and (ii) use this information to develop new exosome-based nanotreatments for diabetes.
We are looking for someone with a genuine interest in interdisciplinary research to understand and ameliorate human metabolic diseases. Previous experience in cell culture and molecular biology is desirable but not essential, as are coding skills.
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