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Development and application of ultra-high frame rate imaging approaches to investigate circuit mechanisms for memory-related network oscillations

College of Medicine and Veterinary Medicine

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Prof M Nolan , Dr Istvan Gyongy , Dr S Mitra No more applications being accepted Competition Funded PhD Project (Students Worldwide)

About the Project

Deanery of Biomedical Sciences

Learning and memory are associated with oscillations in the activity of neural networks in the hippocampus and its associated structures. Many theories of memory propose key roles for these oscillations in memory storage and retrieval, but testing these ideas requires new approaches to determine the activity of defined neural populations during network oscillations that accompany learning and memory. To address this challenge the project will develop and apply state-of-the-art tools to enable kilohertz frame rate imaging of neural activity reported by genetically encoded voltage sensors targeted to specific neural populations.

The project will provide training in the development of imaging tools and cutting edge methods for systems neuroscience. The project will be well suited to candidates aiming to apply engineering skills to neuroscience questions, or to candidates with a strong background in neuroscience who wish to contribute to development of transformative new technologies. All candidates should aim to contribute to a new understanding of brain function and provide a foundation for novel future investigations of brain disorders.

This 4 year PhD project is part of a competition funded by EASTBIO BBSRC Doctoral Training Partnership. This opportunity is open to UK and international students and provides funding to cover stipend and UK level tuition fees. The UoE covers the difference between home and international fees. There is a cap on the number of international students the DTP can recruit so it is important to know in which fees status category applicants fall under when applying.

Refer to UKRI website and Annex B of the UKRI Training Grant Terms and Conditions for full eligibility criteria.

Funding Notes

Application Procedure
Download application and reference forms from

Completed application form along with your supporting documents should be sent to our PGR student team at [Email Address Removed] by 6th January 2021.

References: Please send the reference request form to two referees. Completed references for this project should also be returned to [Email Address Removed] by the closing date: 6th January 2021.

It is your responsibility to ensure that references are provided by the specified deadline.
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