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Development of a novel immunotoxin

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

Immunotoxins represent a form of immunotherapy whereby antibodies are used to target a toxin, usually to cancer or infected host cells. However, to date, their clinical use has been limited in part due to dose-limited toxicity. We have recently indentified a novel toxin, which exhibits selectivity for rapidly dividing cells and is not taken up by most normal cells. We have shown that we can target the toxin to cancer cell lines using specific antibodies and that it inhibits their growth. The project will involve the further development and improvement of the immunotoxin.

Science Graduate School

As a PhD student in one of the science departments at the University of Sheffield, you’ll be part of the Science Graduate School – a community of postgraduate researchers working across biology, chemistry, physics, mathematics and psychology. You’ll get access to training opportunities designed to support your career development by helping you gain professional skills that are essential in all areas of science. You’ll be able to learn how to recognise good research and research behaviour, improve your communication abilities and experience technologies that are used in academia, industry and many related careers. Visit http://www.sheffield.ac.uk/sgs to learn more.

Funding Notes

Entry requirements
First class or upper second 2(i) in a relevant subject. To formally apply for a PhD position, you must complete the University's application form using the following link: View Website

*All applicants should ensure that both references are uploaded onto their application as a decision will be unable to be made without this information*.

How good is research at University of Sheffield in Biological Sciences?

FTE Category A staff submitted: 44.90

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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