Development of Adaptive Metallosupramolecular Cages

A fully funded PhD studentship is available in the group of Dr. Pike at the University of Birmingham in area of synthetic supramolecular chemistry focused on the development of a new range of adaptive metallosupramolecular cages. Metallosupramolecular cages that can demonstrate host-guest chemistry, within their central cavities, are the subject intense interest due to their widespread applications in sensing and catalysis and for their ability to act as small-molecule delivery devices. The development of metallosupramolecular cages that are able to exhibit control over the binding event of the host-guest chemistry are highly sought after as they have the potential to regulate these applications, for example by switching off or on sensing of specific molecules. The aim of this PhD project is to develop a new range of metallosupramolecular cages that can adapt their properties in a highly controlled manner, in order to exploit responsive host-guest chemistry, for a range of important functional outputs including the sensing of biologically important molecules. The researcher will develop skills in organic synthesis, supramolecular self-assembly processes and a range of analytical techniques (including NMR spectroscopy, UV/Vis and IR spectroscopy and mass spectrometry). Candidates should have an interest in or experience in synthetic organic and supramolecular chemistry. This studentship is only open to UK or EU nationals. By the start of their appointment, the successful applicant should possess a good (1st or 2.1 UK or equivalent) degree in chemistry. Interested candidates should contact Dr. Sarah Pike ([Email Address Removed]) in the first instance by email, attaching an up-to-date CV. Anticipated Start Date: 1st October 2020