Development of Advanced EndoSpectroscopic Sensing (EndSpec-Sens) and Monitoring Device for Inflammatory Bowel Disease: From tissue and biofluid discovery, through early-stage diagnostics and onto personalised therapy

The PhD project is of a highly interdisciplinary nature, and lies at the interface between biomedical engineering, biosciences and medicine. It will focus on developing and engineering new methods for improved, accurate detection and assessment of Inflammatory Bowel Disease (IBD) lesions and tissue healing as well as understanding, monitoring and controlling the cellular

and tissue responses to therapeutical treatments. The research will include development and engineering of novel, integrated endoscopic and Raman techniques and tailored microfluidic lab-on-a-chip to enable early-detection of IBD and its disease activity, neoplastic changes and healing at nearly histological level and delivery of successful stratification and tailored therapy to individual patients. By restoring and maintaining diseased tissue and organs, the outcome of this research will lay a platform towards revolutionizing the ways we improve the health and quality of life for millions of people worldwide.

This PhD project is part of CDT in Engineered Tissues for Discovery, Industry and Medicine, a partnership between the University of Glasgow, University of Birmingham, Aston University and National University of Ireland Galway. The CDT will train the next generation of interdisciplinary (engineering, chemistry, physics, maths and biology) leaders in developing in vitro tissues, sensing and diagnostics to develop humanised in vitro systems to drive better drug screening.

For more information about the benefits of the programme, funding, eligibility and EDI support please refer to our main CDT advert.