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Development of long-acting drug delivery platform (LADDP) to treat chronic disorders

School of Pharmacy

Belfast United Kingdom Pharmaceutical Chemistry Pharmacy

About the Project

LADDPs can offer significant advantages over traditional delivery systems by reducing the frequency of drug administration such as in the treatment of cancer, schizophrenia and pain. The LADDPs can result in improved patient compliance, cost savings for the healthcare and adherence – thereby providing better therapeutic outcomes.

During this research project the student will work on in situ depot forming injectable LADDP, which will involve synthesis and characterisation of novel polymers; physico-chemical and mechanical characterisation of depot forming implants. Develop models to investigate implant degradation. Develop a range of analytical techniques for testing the compatibility of molecules with polymeric matrices, investigate factors affecting drug loading and in vitro release. The student will also be involved in developing bespoke ex vivo disease models to test the implant performance.

Funding Notes

Applicants should have a 1st or 2.1 honours degree (or equivalent) in a relevant subject. Relevant subjects include Pharmacy, Pharmaceutical Sciences, polymer science, chemical engineering or a closely related discipline. Students who have a 2.2 honours degree and a Master’s degree may also be considered, but the School reserves the right to shortlist for interview only those applicants who have demonstrated high academic attainment to date.


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