Development of nanomaterials as Magnetic Resonance Imaging (MRI) Contrast agents (using Organic Chemistry, Chemical Biology and Materials Science)

A fully funded 3-year PhD studentship is available in UCL Chemistry to work on a highly interdisciplinary project in the groups of Dr Vijay Chudasama (60%) and Dr Gemma-Louise Davies (40%). The project will involve: (i) the synthesis of small molecules and their application in the site-selective modification of proteins, (ii) the development of nanostructured materials as Magnetic Resonance Imaging (MRI) contrast agents, and (iii) the controlled attachment of the site-selectively modified proteins onto the surface of the nanostructured material. The aim is to target the MRI contrast agents to specific disease targets using state-of-the-art bioconjugation chemistry. The student will gain expertise in synthetic organic chemistry, bioconjugation, inorganic nanoparticle synthetic techniques, and the use of a variety of analytical techniques, including, but not limited to, mass spectrometry, ELISAs, SPR, relaxometry, clinical MRI and electron microscopy.

Please visit our group websites for more details about our research: http://chudasama-group.eu/ and https://gemmalouisedavies.com/

The applicants should have, or expect to gain, at least a 2.1 honours or equivalent at Masters level in Chemistry, or a related discipline. The successful applicant will demonstrate strong interest and self-motivation in the subject and the ability to think analytically and creatively. An enquiring and rigorous approach to research as well as good team-working, observational and communication skills (both presentation and writing skills in English) are also essential. Previous research experience in contributing to a collaborative interdisciplinary research environment is highly desirable but not essential, as training will be provided. UCL offers a world leading scientific environment in the heart of London.

Applicants should send their applications (motivation letter, CV and contact info for 2 referees) by email to Dr Chudasama ([Email Address Removed]), who may also be approached for informal enquiries.

Suitable candidates will be required to complete an electronic application form at http://www.ucl.ac.uk/prospective-students/graduate/apply. Any admissions queries should be directed to [Email Address Removed].