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Development of novel dermatologic applications of in vivo FTIR molecular spectroscopy

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  • Full or part time
    Dr S Danby
    Prof Stephen Matcher
    Prof Michael Cork
  • Application Deadline
    No more applications being accepted
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

Project Description

L’Oreal is the world’s largest personal care company. The Active Cosmetics Division of L’Oreal, comprising the Vichy, La Roche-Posay, SkinCeuticals, Roger & Gallet, CeraVe and Sanoflore brands, is a world leader in dermocosmetics.

Agilent is a leader in life sciences, diagnostics and applied chemical markets. The company provides laboratories worldwide with instruments, services, consumables, applications and expertise, enabling customers to gain the insights they seek. The Spectroscopy Division of Agilent has developed handheld spectroscopy instrumentation which is gaining rapid acceptance in a wide variety of application areas, most recently including skin analysis.

The aim of this project is to develop novel dermocosmetic applications for FTIR spectroscopy using the Agilent 4300 spectrometer. We have already shown that FTIR can be used in vivo to quantify the skin barrier defect in patients with eczema, and that this measurement could potentially help direct preventative therapies towards those most at risk.

Working in partnership with L’Oreal and Agilent the student will undertake a program of research, involving in vivo human skin testing, to develop new analytical methods to quantify skin properties that will help support future product development and testing. The work will be based at Sheffield’s internationally recognised Skin Barrier Laboratory, and will additionally involve a 3-month placement at L’Oreal, where the student will gain a valuable insight into research and development at a world leading cosmetics company.

Funding Notes

Subject to funding for candidates meeting EPSRC studentship eligibility criteria. For more details, please see

The award covers fees and a stipend at the standard UK research rate. The principle industry partner is offering a further £2,000 per annum enhancement of the stipend. The stipend rate is £17,009 per year for 4 years. The stipend is only payable to UK residents.

Entry Requirements:
Candidates should have, or expect to achieve, a first or upper second-class honors degree (2.1 or above) or significant research experience in bio- or biomedical engineering, medical physics, or a related discipline.


Interested candidates should in the first instance contact Dr Simon Danby ([email protected])

How to apply:
Please complete a University Postgraduate Research Application form available here:

Please clearly state the prospective main supervisor in the respective box and select Infection, Immunity & Cardiovascular Disease (IICD) as the department.

Proposed start date: 1 October 2019

Related Subjects

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