Disparities in Type 2 Diabetes: Investigating the Impact of different pharmacotherapeutic agents on Glycaemic Control among Black Population


   Department of Population Health Sciences

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  Prof Samuel Seidu  No more applications being accepted  Competition Funded PhD Project (UK Students Only)

About the Project

Project Description

Start date 1 October 2024

This project addresses Type 2 Diabetes (T2D) disparities among minority ethnic groups, specifically focusing on the black population. Research shows that minority ethnic groups face a higher risk of T2D and experience a more aggressive onset compared to white Caucasians. While T2D in South Asians and white Caucasians has been studied extensively, our understanding of T2D in the black population is limited. The research investigates insulin secretory deficiencies in early-stage T2D among black individuals, possibly linked to beta cell fatigue. The project suggests that early intervention to preserve insulin secretory capacity, like using insulin therapy, may help slow T2D progression in black populations. Surprisingly, the impact of ethnicity on these aspects remains largely unexplored, despite evidence supporting the benefits of early intensive insulin treatment in T2D management. This project aims to assess the impact of T2D, metabolic and anthropometric characteristics, and different therapeutic approaches on glycaemic control among black individuals compared to other ethnic groups. To achieve these, we will use evidence synthesis, qualitative study design, and real-world data analysis, including the Clinical Practice Research Datalink (CPRD). This research can uncover tailored treatment strategies to address T2D disparities and improve long-term glycaemic control in newly diagnosed black individuals with T2D

Entry requirements:

Applicants are required to hold/or expect to obtain a UK Bachelor Degree 2:1 or better in a relevant subject. 

The University of Leicester English language requirements apply where applicable.

Eligibility

This programme is open to:

  • allied health professionals
  • nurses
  • midwives
  • junior doctors
  • general practitioners

Fellows recruited to the programme must be practicing healthcare professionals and be registered with a national professional regulatory body (e.g. the General Medical Council, Health and Care Professions Council) in the UK/Republic of Ireland.

Medical graduates must be registered on a UK/Republic of Ireland specialist training programme or must be a registered GP.

All fellows must have completed their undergraduate degree and be registered with the relevant professional body.

Project / Funding Enquiries to: [Email Address Removed]

Application advice:

Application help:  https://le.ac.uk/study/research-degrees/healthcare-inequalities/application-help.

To apply, please go to: https://le.ac.uk/study/research-degrees/funded-opportunities/leicestershire-healthcare-inequalities-improvement-dtp


Medicine (26) Nursing & Health (27)

Funding Notes

The Wellcome Trust LHII DTP funding will provide:
Funding will cover three years salary for each Fellow
UK Tuition Fees for three years
Experimental research costs and training