Aberdeen University Featured PhD Programmes
National University of Ireland, Galway Featured PhD Programmes
Heriot-Watt University Featured PhD Programmes
University of Southampton Featured PhD Programmes
University of Reading Featured PhD Programmes

Do we have to keep patients in cast and prevent them weight-bearing following internal fixation of ankle fractures?

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Awaiting Funding Decision/Possible External Funding
    Awaiting Funding Decision/Possible External Funding

About This PhD Project

Project Description

Currently, there is a lack of consensus in post-operative management regimes following ORIF of unstable fractures about the ankle leading to a wide variation in clinical practice. There is an evolving understanding that extended periods of immobilisation and limitation of weight-bearing lead to poorer outcomes. The traditional non-weight bearing cast immobilisation was born of a desire to prevent loss of fixation and this practice has continued in many centres. The purpose of the study is to investigate the safety and efficacy of immediate weight-bearing and ROM exercise regimes following ORIF of unstable ankle fractures with a particular focus on functional outcomes and complication rates.


This is a pragmatic randomised-controlled multi-centre trial, comparing immediate weight-bearing and range of motion (ROM) exercise versus non-weight bearing and immobilisation, following open reduction and internal fixation (ORIF) of unstable adults ankle fractures. The primary outcome measure is the ankle function Olerud and Molander Score, secondary outcomes measures include; complication rate, ankle ROM, physical and mental health outcomes SF36, time needed to return to work and postoperative hospitalisation length.


The literature is contradicting when it comes to the assessment of weight-bearing regimens following ankle fracture fixation. Immediate weight-bearing following ankle fracture fixation has not been investigated extensively. This randomised-controlled multi-centre trial will help in formulating a widely accepted guideline for postoperative management of ankle fractures.

Trial registration: 'retrospectively registered' ISRCTN - ISRCTN76410775 30/06/2019


Apply for funding for MD project.


Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here
* required field
Send a copy to me for my own records.

Your enquiry has been emailed successfully

FindAPhD. Copyright 2005-2020
All rights reserved.