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Downstream processing of nano-scale biological raw materials for drug delivery


Chemical Engineering

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Dr Svetlana Ignatova No more applications being accepted Funded PhD Project (UK Students Only)

About the Project

Brunel University London (BUL) is recruiting to EPSRC Doctoral Training Partnership (DTP) PhD studentships effective 1 October 2020. Applications are invited for the following specific project called “Downstream processing of nano-scale biological raw materials for drug delivery”.

The successful applicants will join the internationally recognised researchers in the Department of Chemical Engineering. This exciting research project is focused on enhancement of Medicinal drug delivery by development of scalable processes for the supply of monodisperse biological soft nanoparticles (including viruses, micelles, vesicles and cells). Monodisperse populations ensure both consistent and reproducible release and bioavailability of medicinal drugs to patients. Specifically, the project aims to develop liquid-liquid separation techniques for bionanoparticles by controlled changes to the surface properties based on the size distribution to allow fractionation and separation, both through and within multi-phase liquid-liquid interfaces.

Applicants will be required to demonstrate their ability to conduct biological experiments and assays. Collect, analyse and critically assess data, and develop models for the fractionation processes. More broadly, they will be expected to show critical thinking and good self-management skills

Please contact Dr Svetlana Ignatova at [Email Address Removed] for an informal discussion about the studentships.

Eligibility

Applicants will have or be expected to receive a first or upper-second class honours degree in an Engineering, Chemistry, Mathematics, Physics or a similar discipline. A Postgraduate Masters degree is not required but may be an advantage.

Experience in bioprocess or chemical engineering downstream processing, with knowledge of bio assays and recent advances in bio-separation and fractionation methods is an advantage. In addition, applicants should be highly motivated, able to work independently as well as part of a team, collaborate with others and have good communication skills.

How to Apply

Please submit your application documents (see list below) by Noon on Friday 26 June 2020 to [Email Address Removed] Interviews will take place in July 2020.
• Your up-to-date CV;
• Your personal statement (300 to 500 words) summarising your background, skills and experience;
• Your Undergraduate/Postgraduate Masters degree certificate(s) and transcript(s);
• Evidence of your English language skills to IELTS 6.5 (or equivalent, 6.0 in all sections), if appropriate;
• Contact details for TWO referees, one of which can be an academic member of staff in the College.

Remember to state the title of the project at the top of your personal statement.

Funding Notes

Successful applicants will receive an annual stipend (bursary) of £17,285 plus payment of their full-time home tuition fees for a period of 36 months (3 years). Applicants must be eligible for home tuition fees either through nationality, residency (living in the UK for at least three years and not wholly for educational purposes) or other connection to the UK.
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