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Drug Discovery: the Next Generation

   Department of Chemistry

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  Prof Tony James  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

The University of Bath is inviting applications for the following PhD project commencing in October 2022 under the supervision of Professor Tony James in the Department of Chemistry.

Eligible applicants will be considered for a fully-funded studentship – for more information, see the Funding Notes section below.

Overview of the Project:

Throughout medical history, the most common diagnostic approach has been to react to an obvious sign that something is wrong. This means an individual patient must wait until the onset of a particular disease (i.e. cancer) before an appropriate diagnosis is possible. This process is further slowed by extensive clinical examinations, clinical imaging, and physician-to-patient discussions. Finally, therapeutic evaluation cannot be appraised until the patient has undergone the complete course of treatment. This time-consuming process can prove detrimental as it can reduce the success of a patient’s treatment plan and chances of remission or recovery.

The aim of this project is to develop therapeutic systems that can simultaneously enhance our understanding of disease progression and allow real-time treatment We will implement a new way of thinking for drug design and development, with structure activity relationship studies (SARs) focused on optimising a drug’s therapeutic and fluorescent properties.

During the project you will develop

  1. fluorescent therapeutics that can provide information on the biological location of a drug;
  2. fluorescent theranostics designed to respond to biological analytes for disease diagnostics as well as provide a therapeutic effect.

Project keywords: drug discovery, synthesis, therapeutics, health and wellbeing.

Candidate Requirements:

Applicants should hold, or expect to receive, a First Class or good Upper Second Class Honours degree (or the equivalent) in Chemistry and possess a interest in synthetic chemistry. A master’s level qualification would also be advantageous.

Non-UK applicants must meet our English language entry requirement.

Enquiries and Applications:

Informal enquiries are welcomed and should be directed to Professor Tony James (email: [Email Address Removed]).

Formal applications should be made via the University of Bath’s online application form for a PhD in Chemistry.

More information about applying for a PhD at Bath may be found on our website.

Equality, Diversity and Inclusion:

We value a diverse research environment and aim to be an inclusive university, where difference is celebrated and respected. We welcome and encourage applications from under-represented groups.

If you have circumstances that you feel we should be aware of that have affected your educational attainment, then please feel free to tell us about it in your application form. The best way to do this is a short paragraph at the end of your personal statement.

Funding Notes

Candidates applying for this project may be considered for a 3.5-year Engineering and Physical Sciences Research Council (EPSRC DTP) studentship. Funding covers tuition fees, a stipend (£15,609 per annum, 2021/22 rate) and research/training expenses (£1,000 per annum). EPSRC DTP studentships are open to both Home and International students; however, in line with guidance from UK Research and Innovation (UKRI), the number of awards available to International candidates will be limited to 30% of the total.


Chem. Soc. Rev., 2021,50, 9391-9429
Chem. Soc. Rev., 2021,50, 702-734
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