About the Project
Open until the position is filled
The candidate should have a first class or upper second class honours degree, or a master’s degree (or equivalent qualification), in Chemistry. Evidence of good spoken and written English is essential. The candidate should have an IELTS score of 6.5 or above, if the first language is not English. This position is open to all qualified candidates irrespective of nationality.
The student will be awarded a PhD degree from the University of Liverpool (UK) upon successful completion of the program.
Hepatitis C virus is the cause of Hepatitis C, a major infectious disease that induces liver inflammation and cirrhosis. Recently, the first generation of Directly Acting Antivirals has been developed, which inhibit specific virus enzymes, with the main target being NS3/4A protease. The high co-occurrence of HepC/HIV infection prompted us to investigate the possibility of developing dual inhibitors for the HIV-I and NS3/4A proteases, i.e. targeting both diseases at one stroke. HIV/AIDS is one of the most devastating global diseases, with proteolytic processing of the viral polyprotein responsible for the generation of the mature, infectious species. Based on these facts, and given the remarkable properties of the phosphinic binding group, we have set out to develop enzyme inhibitors based on phosphinic peptides, which would simultaneously target the NS3/4A protease of HepC and the HIV-1 protease. Our preliminary results are highly encouraging.
For more information about doctoral scholarship and PhD programme at Xi’an Jiaotong-Liverpool University (XJTLU): Please visit
How to Apply:
Interested applicants are advised to email [email protected] (XJTLU principal supervisor’s email address) the following documents for initial review and assessment (please put the project title in the subject line).
• Two reference letters with company/university letterhead
• Personal statement outlining your interest in the position
• Proof of English language proficiency (an IELTS score of 6.5 or above)
• Verified school transcripts in both Chinese and English (for international students, only the English version is required)
• Verified certificates of education qualifications in both Chinese and English (for international students, only the English version is required)
• PDF copy of Master Degree dissertation (or an equivalent writing sample) and examiners reports available
Informal enquiries may be addressed to Dr. Magdalini Matziari ([email protected]), whose personal profile is linked below,
Why not add a message here
Based on your current searches we recommend the following search filters.
Based on your current search criteria we thought you might be interested in these.
Assessing the hemodynamic signal sources of fMRI based spontaneous connectivity maps and how neuronal plasticity such as increased spatial working memory can change these networks
University of Sheffield