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Early PI3-mediated translation response during intracellular bacterial and viral infection

  • Full or part time
  • Application Deadline
    Thursday, January 03, 2019
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

Biotic stresses often occur on short timescales, making rapid response crucial for survival of both host and pathogen. Cells respond to stress by regulating gene expression at multiple steps but especially transcription, translation and protein turnover. Transcriptional regulation is generally more versatile; however translational regulation of pre-existing mRNA is faster and more efficient, as it circumvents de novo mRNA transcription, processing and transport to the cytoplasm. This project aims toward understanding the complex interplay of host- pathogen gene regulation at the translational levels, and their ultimate effect of the major immune cell for innate immunity in response to biotic stress.

Full details of the projects and how to apply are available from the following link:
*Please quote reference PK17049 on your application and in any correspondence about this vacancy.

Funding Notes

The studentships are available to students who qualify for Home/EU fees. Further information at: View Website.

Funding will cover the student's stipend at the current Research Council rate and University Fees. The studentships will be funded for three years in the first instance subject to eligibility with the possibility of additional funding in the fourth year depending on circumstances.

Applicants should hold or be about to achieve a First or Upper-Second (2.i) class degree in a relevant subject.
By time of interview all potential students must have fulfilled language requirements for admission.
(View Website).

Applications from ineligible candidates will not be considered.

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