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EASTBIO: Friend or Foe: Establishing genetic factors that control niche adaptation in Klebsiella variicola


   College of Medicine and Veterinary Medicine

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  Dr T Schneiders, Dr N Holden, Dr Refath Farzana  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

Klebsiella spp. inhabit multiple niches which attests to its’ wider ecological distribution and genetic and metabolic plasticity, in addition to high rates of antibiotic resistance and virulence. K. variicola, which is a subspecies within the Klebsiella genus, occupies multiple niches ranging from plantendophytism to pathogenic behaviour in plants, humans and animals. Given the emerging relevance of K. variicola in both human and plant health, it is critical we undertake a targeted molecular approach in studying this species. Existing genomic data of Kv population structure do not immediately identify factors which facilitate niche adaptation and infection. Therefore, the overarching goal of this project is to establish in vivo infection models to biologically validate factors which underpin Kv niche adaptive traits and lifestyle.


Funding Notes

Application Procedure
Download application and reference forms from http://www.eastscotbiodtp.ac.uk/how-apply-0
Completed application form along with your supporting documents should be sent to our PGR student team at [Email Address Removed] by 16 December 2021. Unfortunately due to workload constraints, we cannot consider incomplete applications.
References: Please send the reference request form to two referees. Completed references for this project should also be returned to [Email Address Removed] by the closing date: 16 December 2021.
It is your responsibility to ensure that references are provided by the specified deadline.
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