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Economic evaluation of antenatal corticosteroid therapy prior to planned caesarean section at late preterm and term gestational ages


Liggins Institute

About the Project

Birth by planned caesarean section compared to planned vaginal birth increases the risk of neonatal respiratory morbidity and the need for babies to be admitted to a neonatal unit.

Use of antenatal corticosteroids in women undergoing planned caesarean section at term or late preterm is supported by findings of improved neonatal respiratory morbidity in a limited number of randomised trials but may increase the risk of neonatal hypoglycaemia.

We are undertaking a large Health Research Council funded multicentre placebo-controlled trial to assess both the neonatal benefit and potential harm of maternal corticosteroid use prior to planned caesarean section at ≥35+0 to 39+6 weeks.

We aim to explore the effect of cost-effectiveness of this intervention as well as explore its potential health benefits.
What we are looking for in a successful applicant

Objective:

To use data from the C*STEROID Trial to examine the cost-effectiveness of the use antenatal corticosteroids prior to planned caesarean section at term and late preterm gestations.

More about the C*STEROID Trial: https://www.auckland.ac.nz/en/liggins/in-the-community/clinical-studies/clinical-studies-pregnancy/c-steroid-feasibility-study.html

Funding Notes

Scholarships may be available for this project and can be discussed with the potential supervisor.

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