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Effective and efficient conduct of miscarriage trials: A study of four large multi-centre trials

Project Description

The University of Birmingham is the leading partner of Tommy’s National Centre for Miscarriage Research, the largest miscarriage research centre in Europe. In collaboration with clinicians at Birmingham Women’s and Children’s Hospital NHS Foundation Trust and around the country, we aim to save babies’ lives by turning scientific discoveries into important tests and treatments. An important component of the research is clinical trials, which are conducted in collaboration with the Birmingham Clinical Trials Unit, the largest NIHR-funded trials units in the UK. The Centre has completed the PROMISE, AIMS, PRISM and TABLET trials, and is currently conducting the MifeMiso and LOCI trials.

The successful applicant for this role will work with Dr Adam Devall, Professor Arri Coomarasamy, Dr Ioannis Gallos and Dr Hannah Jeffery to elucidate the most effective strategies for the efficient conduct of clinical trials.


1. Analyse the existing data from four large multi-centre trials to identify efficient trial conduct practices.
2. Explore methods for accelerated trial development and conduct.
3. Investigate the potential use of routinely collected data to validate and collect clinical trial outcome data.

Person Specification

Applicants will be based in the University of Birmingham Academic Department at Birmingham Women’s Hospital.
The position is for a 3-year fully-funded PhD Studentship starting September 2019.

How to apply

Informal enquiries should be directed to:
Professor Arri Coomarasamy, Professor of Gynaecology and Director of Tommy’s National Centre for Miscarriage Research

To be considered for this studentship, please send the following documents to Viktorija Ziabliceva ():

• A detailed CV, including your nationality and country of birth;
• Names and addresses of two referees;
• A covering letter highlighting your research experience/capabilities;
• Copies of your degree certificates with transcripts;
• Evidence of your proficiency in the English language, if applicable.

Funding Notes

Funding is available to cover the full cost of tuition fees and yearly stipend over the course of the PhD programme for students of either British or EU nationality.

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