ElectroLumina : Illuminating the Electrifying Future of Drug Manufacturing - [Synthetic Organic ElectroSynthesis] at University of Greenwich on FindAPhD.com

This project is no longer listed on FindAPhD.com and may not be available.

Click here to search FindAPhD.com for PhD studentship opportunities

Prof Kevin Lam No more applications being accepted Funded PhD Project (European/UK Students Only)

London United Kingdom Analytical Chemistry Applied Chemistry Industrial Chemistry Inorganic Chemistry Organic Chemistry Chemistry Pharmaceutical Chemistry Physical Chemistry Structural Chemistry Synthetic Chemistry

About the Project

Funding note: The grant will cover the Home (UK, EU (pre)-settled and Ireland) tuition fees and offer a stipend in line with UKRI. Non-UK/IE/EU applicants are welcome, but funding will cover only the home tuition fees, and the international applicant will have to secure additional funding to cover the difference between the home tuition and the international tuition fees + the visa fees.

In addition, the grant provides the student with a standard UKRI stipend.

About the Project

In this project, we will develop a unique approach to generating highly reactive intermediates using electrochemistry and photochemistry. These will be used to prepare pharmaceutically relevant compounds that will be biotested. Finally, as a proof of concept, in collaboration with industries such as GSK, AZ or Merck, we will scale up the newly developed processes using flow chemistry.

We are now looking for highly motivated PhD students to join our team and further explore the synthetic potential of organic electrosynthesis.

The candidate:

The projects would be suitable for a student with a strong background in synthetic chemistry and an interest in electrochemistry.

The Student will be supervised by Dr Kevin Lam (http://www.lamresearchgroup.com) and join a group of young, international and dynamic researchers!

Why join our research group? http://www.lamresearchgroup.com

1. Innovative research: Be at the forefront of scientific discovery by working on a unique and interdisciplinary project that has the potential to revolutionise the field of chemistry.

2. State-of-the-art facilities: Our laboratory is exceptionally well equipped with 16 Electrasyns, its own electrochemical glovebox, as well as its own GC-MS and HPLC-MS, automated chromatography systems and full access to 4 NMR spectrometers and high-resolution mass spectrometers.

3. Expert mentorship: Learn from and collaborate with Dr Kevin Lam (electrosynthesis), Dr Xacobe Cambeiro (Photochemistry) and Dr Sweta Ladwa (Medicinal Chemistry and Biotesting), an accomplished team of researchers and leaders in their fields.

4. Industry Collaboration: Gain valuable experience working with leading pharmaceutical companies such as GSK, AstraZeneca and Merck, giving you a competitive edge in your future career.

5. Supportive environment: Join a diverse and inclusive research group that values collaboration, innovation and personal development.

Requirements:

- Strong background in synthetic organic chemistry. A focus on electrosynthesis, photosynthesis, flux chemistry or related areas is not necessary but would be an advantage.

- A Bachelor or Master degree in chemistry or a closely related discipline.

- Excellent communication and problem-solving skills.

- A passion for research and a strong desire to contribute to advancing the field.

How to apply:

To apply for this exciting opportunity, please submit the following documents to Dr Kevin Lam

1. A cover letter detailing your research interests, motivation for pursuing a PhD and how your background fits the project.

2. A detailed curriculum vitae including academic qualifications, research experience and any relevant publications or presentations.

3. Contact details of two academic referees who can comment on your research skills and potential.

Don't miss the chance to be part of a cutting-edge research group and make a lasting impact on the world of chemistry. Apply now and take the first step towards an exciting and fulfilling research career!

Funding Notes

The scholarships cover full tuition fees for home students (£4,500) and a non-taxed yearly stipend (£17,700), providing a fantastic opportunity to pursue your PhD without financial burden. International students are welcome to apply but will need to cover the difference in tuition fees (approximately £12,500 per year).
The project:

References

1. Leech, M., Nagornii, D., Walsh, J, Kiaku,C, Poole, D., Mason, J., Goodall, I. Devo, P, Lam, K.*, eFluorination Using Cheap and Readily Available Tetrafluoroborate Salts. Org. Lett., 2023, https://doi.org/10.1021/acs.orglett.2c04305.
2. Kiaku, C., Walsh, J. M., Leech, M. C., Poole, D. L., Mason, J., Goodall, I. C. A., Devo, P., Lam, K.* Electrochemical Isothiocyanation of Primary Amines. Org. Lett., 2023. https://doi.org/10.1021/acs.orglett.3c00128.
3. Tanbouza, N., Petti, A., Leech, M. C., Caron, L., Walsh, J. M., Lam, K.*, Ollevier, T. Electrosynthesis of Stabilized Diazo Compounds from Hydrazones. Org. Lett., 2022, https://doi.org/10.1021/acs.orglett.2c01803
4. Leech, M. C.; Lam, K.* A practical guide to Electrosynthesis. Nature Reviews Chemistry, 2022, 1–12. https://doi.org/10.1038/s41570-022-00372-y
5. Garcia, A. D.; Leech, M. C.; Petti, A.; Denis, C.; Goodall, I. C. A.; Dobbs, A. P.; Lam, K.* Anodic Oxidation of Dithiane Carboxylic Acids: A Rapid and Mild Way to Access Functionalized Orthoesters. Org. Lett. 2020, 22 (10), 4000–4005. https://doi.org/10.1021/acs.orglett.0c01324.
6. Quertenmont, M.; Goodall, I.; Lam, K.*; Markó, I.; Riant, O. Kolbe Anodic Decarboxylation as a Green Way to Access 2-Pyrrolidinones. Org. Lett. 2020, 22 (5), 1771–1775. https://doi.org/10.1021/acs.orglett.0c00056.
7. Petti, A.; Leech, M. C.; Garcia, A. D.; Goodall, I. C. A.; Dobbs, A. P.; Lam, K.* Economical, Green, and Safe Route Towards Substituted Lactones by Anodic Generation of Oxycarbonyl Radicals. Angew. Chem. Int. Ed. 2019, 58 (45), 16115–16118. https://doi.org/10.1002/anie.201909922.