University of Leeds Featured PhD Programmes
Norwich Research Park Featured PhD Programmes
Norwich Research Park Featured PhD Programmes
Engineering and Physical Sciences Research Council Featured PhD Programmes
The Hong Kong Polytechnic University Featured PhD Programmes

Electrosynthesis - Exploring the Potential of Electrogenerated Radicals!

  • Full or part time
  • Application Deadline
    Saturday, February 01, 2020
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

Electrosynthesis is a powerful tool in organic chemistry that circumvents the use of expensive and toxic reagents for the generation of reactive intermediates. During electrosynthesis, molecules are activated under mild and green conditions directly at the surface of an electrode. Even though a plethora of transformations have been developed, and many of them were successfully used in several industrial processes the potential of preparative organic electrochemistry remains largely underestimated. However, the growing impetus to look for greener and cheaper alternatives to classic synthetic methodologies prompted us to investigate further new electrochemical reactions.


We have recently developed two novel electrochemical methodologies that allow generating organic and organometallic radicals under mild, green, economical and safe conditions. We have successfully applied those methodologies to the preparation of new types of anticancer drugs.

We are now looking for highly motivated PhD Students to join our team and explore further the synthetic potential of these radicals.

The candidate:
The project would be suitable for a student with a strong background in synthetic chemistry and interest in medicinal chemistry and electrochemistry.
The Student will be supervised by Dr Kevin Lam (http://www.lamresearchgroup.com) as well as by two post-docs and 7 PhD students.


The Laboratory
The Lam Group is housed within a newly refurbished laboratory and is very well equipped with more than 10 Electrasyns 2.0, a glovebox, a solvent purification system, several automatic chromatography columns, a GC-MS, etc.
Also, the University will provide the Student with routine access to 4 NMR spectrometers, several UPLC-MS, a high-resolution mass spectrometer, MALDI-TOF, etc.

Funding Notes

We kindly ask the Student to identify a suitable funding source, we will then work together to secure it.

References

A. Petti, M. C. Leech, A. D. Garcia, I. C. A. Goodall, A. P. Dobbs and K. Lam, Angew. Chemie Int. Ed., 2019 , DOI:10.1002/anie.201909922.

C. G. W. van Melis, M. R. Penny, A. D. Garcia, A. Petti, A. P. Dobbs, S. T. Hilton and K. Lam, ChemElectroChem, 2019, DOI:10.1002/celc.201900815.

X. Luo, X. Ma, F. Lebreux, I. E. Markó and K. Lam, Chem. Commun., 2018, 54, 9969–9972.

Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here
* required field
Send a copy to me for my own records.

Your enquiry has been emailed successfully





FindAPhD. Copyright 2005-2019
All rights reserved.